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原发性甲状腺功能减退致反应性垂体增生的诊断和处理
引用本文:李永宁,陶蔚,杨义,马文斌,任祖渊,苏长保,王任直. 原发性甲状腺功能减退致反应性垂体增生的诊断和处理[J]. 中国微侵袭神经外科杂志, 2005, 10(1): 14-15
作者姓名:李永宁  陶蔚  杨义  马文斌  任祖渊  苏长保  王任直
作者单位:中国医学科学院中国协和医科大学北京协和医院神经外科,北京,100730
摘    要:目的探讨原发性甲状腺功能减退致垂体反应性增生的诊断和处理原则。方法回顾性分析5例确诊病人的临床资料。结果均为原发性甲状腺功能减退症,MRI示垂体占位,直径1.2~2.1 cm。经甲状腺素替代治疗,2~4个月后MRI示垂体恢复正常4例,垂体占位明显缩小1例;血浆甲状腺素水平、促甲状腺素(TSH)和泌乳素(PRL)水平恢复正常。结论原发性甲状腺功能减退病人可以伴有垂体占位,首选激素替代治疗,而不宜行垂体手术。

关 键 词:甲状腺功能减退症  垂体  增生  诊断  治疗
文章编号:1009-122X(2005)01-0014-02
修稿时间:2004-12-15

Diagnosis and management of pituitary hyperplasia due to primary hypothyroidism
LI Yongning,TAO Wei,YANG Yi,et al. Diagnosis and management of pituitary hyperplasia due to primary hypothyroidism[J]. Chinese Journal of Minimally Invasive Neurosurgery, 2005, 10(1): 14-15
Authors:LI Yongning  TAO Wei  YANG Yi  et al
Affiliation:LI Yongning,TAO Wei,YANG Yi,et alDepartment of Neurosurgery,Peking Union Medical College Hospital,Chinese Academy of Medical Science & Peking Union Medical College,Beijing 100730,China
Abstract:Objective To discuss the diagnosis and management of pituitary hyperplasia due to primary hypothyroidism. Methods Five cases were studied retrospectively. Results All patients suffered from primary hypothyroidism. MRI showed pituitary mass, the diameter was 1.2~2.1cm. Thyroxine substitution therapy was given, MRI showed normal pituitary in 4 cases, and decrease of pituitary mass in 1 case after 2~4 months. Plasma thyroxin, TSH and PRL were normal. Conclusion Primary hypothyroidism could induce pituitary mass. Thytoxine substitution therapy was the first line treatment, and unnecessary surgery and other treatment should be avoided.
Keywords:hypothyroidism  pituitary hyperplasia  
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