| 急性冠脉综合征患者血清尿酸与血清NO的相关性 |
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| 引用本文： | 陈炳华,陈德超,袁智勇,张绍荣,周柳嫦,王蔚浩,胡浩荣,顾金保.急性冠脉综合征患者血清尿酸与血清NO的相关性[J].中国当代医药,2010,17(35):9-10. |
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| 作者姓名： | 陈炳华 陈德超 袁智勇 张绍荣 周柳嫦 王蔚浩 胡浩荣 顾金保 |
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| 作者单位： | [1]广东省东莞市常平医院内科,广东东莞523573 [2]南方医科大学公共卫生与热带医学学院病原生物学系,广东广州510515 |
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| 基金项目： | 广东省东莞市2008年度科技计划项目 |
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| 摘 要： | 目的：探讨急性冠脉综合征急性期血清尿酸水平与一氧化氮（NO）的相关性。方法：对纳入的39例ACS患者按血清尿酸浓度高低分为A、B、C3组,以健康人群体检共31例为正常对照组,检测血清NO的变化。结果：尿酸值越高NO值越低,尿酸大于421μmol/L时更为显著,P〈0.001。结论：血清尿酸升高与ACS的发生发展和预后密切相关。
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| 关 键 词： | 急性冠脉综合征（ACS） 血清尿酸 一氧化氮（NO） |
The investigation of the relationship between the concentration of acute-term serum uric acid, Nitric Oxide (NO) to the patients with acute coronary syndrome(ACS) |
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| Authors: | CHEN Binghua CHEN Dechao YUAN Zhiyong ZHANG Shaorong ZHOU Liuchang WANG Weihao HU Haorong GU Jinbao |
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| Institution: | (Department of Cardiology, Changping Hospital of Dongguan City, Guangdong Province, Dongguan 523573, China; 2.Teaching Assistant, School of Public Health and Tropical Medicine, Southern Medical University, Guangdong Province, Guangzhou 510515, China) |
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| Abstract: | Objective： To investigate the relationship between the concentration of acute-term serum uric acid, Nitric Oxide（NO） to the patients with acute coronary syndrome（ACS）. Methods： 39 cases of patients with ACS were divided into A,B,C three groups from low to high concentration as experimental groups, and another 31 cases of healthy crowd as a control group. All patients were detected for the concenlration of serum uric acid and NO. Results： Compared with the control group, as the concentration of uric acid higher, the concentration of NO was lower, when the uric acid was bigger than 421 μmol/L, that was more remarkable, P0.001. Conclusion： The rise of the concentration of serum uric acid showes close relationship with the occurrence or development and the prognosis of ACS. |
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| Keywords: | Acute coronary syndrome（ACS） Sernm uric acid Nitric Oxide（NO） |
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