乙酸铜对黄鳝白细胞及过氧化氢酶活性的影响

目的以黄鳝为材料研究不同浓度的乙酸铜对黄鳝外周血白细胞数目、肝脏过氧化氢酶(CAT)活性的影响。方法采用鱼类致突变实验方法，以0．25，1．00，3．00，9．00，15．00，30．00mg／kg不同剂量乙酸铜处理黄鳝。结果在低剂量范围内，随着乙酸铜剂量的增加黄鳝外周血白细胞的数目下降，而CAT活性升高；至1．00mg／kg时白细胞的数目达最低值，至3．00mg／kg剂量时CAT活性达最大值；剂量再增加，白细胞的数目上升、CAT活性下降。结论一定剂量乙酸铜能明显影响黄鳝外周血白细胞数目及CAT活性，且乙酸铜的作用具有双向性。

Effect of Cu (CH3COO)2 on WBC and CAT activity in monopterus albus

Objective To study the influence of the different concentration of Cu (CH_3COO)_2 on the number of WBC and CAT activity of liver in monopterus albus.Methods The test of fish mutagenesis was used to assay the rate of micronucleus and nuclear anomaly in peripheral blood erythrocytes of monopterus albus as mutagen of 0.25,1.00,3.00,9.00,15.00 and 30.00?mg/kg Cu (CH_3COO)_2.Results With the dosage increase,the number of WBC descended gradually from 0.25 to 1.00?mg/kg,which was the lowest on the dosage of 1.00?mg/kg.When the dosage increased,the number of WBC increased from 1.00 to 30.00?mg/kg.CAT activity from 0.25 to 3.00?mg/kg increased gradually,which were the highest on the dosage of 3.00?mg/kg.When the dosage increased,CAT activity descended from 3.00 to 30.00?mg/kg.Conclusion Some dosages of Cu (CH_3COO)_2 had marked effect on the number of WBC and CAT activity in the peripheral blood cell of monopterus abus,and Cu (CH_3COO)_2 had the effect of two sides.