黄芪丹参滴丸治疗冠心病心绞痛的临床研究

目的评价黄芪丹参滴丸治疗冠心病心绞痛(气虚血瘀证)的临床疗效和安全性.方法采用随机、双盲双模拟、阳性药平行对照、多中心临床研究方法,将209例受试者分试验组104例(黄芪丹参滴丸),对照组105例(养心氏片).结果黄芪丹参滴丸治疗心绞痛的显效率为43.27%,总有效率为86.53%;对中医症状的总有效率92.31%,黄芪丹参滴丸组优于对照组(P＜0.01).结论黄芪丹参滴丸治疗冠心病心绞痛(气虚血瘀证)疗效确切,未发现毒副作用.

Clinical Study of Huangqi Danshen Drop Pill for Angina Pectoris Due to Coronary Heart Disease

Objective To evaluate the therapeutic effect and safety of Huangqi Danshen Drop Pill (HDP) for angina pectoris (AP) due to coronary heart disease (CHD) classified as qi- deficiency and blood- stasis syndrome. Methods A multi- center, randomized, double- blind, double- simulation, positive- controlled, parallel group trial was adopted. 209 cases of AP due to CHD classified as qi- deficiency and blood- stasis syndrome were enrolled in this study: 104 in HDP group and 105 in Yangxinshi Tablets group. Results The markedly effective rate was 43.27 % , total effective rate 86.53 % , and total effective rate in improving TCM symptoms 92.31 % in HDP group, which were better than those in Yangxinshi Tablets group(P < 0.01). Conclusion HDP has definite effect for the treatment of AP due to CHD classified as qi- deficiency and blood- stasis syndrome, having no toxic and side effects.