肝癌术后复发的可能原因及阻断研究

目的 分析肝癌术后复发的可能原因,探讨阻断术后复发方法。方法 通过６８例肝癌术后复发的临床观察,分析肝癌发的相关因素。如果 ６８例肝癌术后复发时间１￣２６个月,平均４．８个月,其中半年内复发者４０例（５８．８２％）。引起复发原因,除手术挤压肝组织引起癌细胞游移外,手术创伤激活细胞因子等,促进机体肝组织各种细胞加速分裂、增殖是重要原因。结论 最大限度减轻手术创伤引起机体的生物学应激反应,可能对降低复

Possible reason for relapse of hepatoma and intervening study on it in post-operative patients

Objective To analyze the possibal reasons for relapse of hepatoma after operation, and discuss the pathways to stop its relapse. Methods The factors correlating with hepatoma relapse after operation were analyzed through clinical investigation of 68 patients with hepatoma relapse after operation. And the effective pathways to prevent hepatoma relapse were discussed. Results 68 cases all relapsed, the time of relapse was 1 month to two years and two months. The mean is 4.8 months,and there were 40 patients(58. 82% ) relapsed within half a year. To analyze the possible reasons that cause hepatoma relapsed suggested that operation damage activated cytokines to promote hepatocyte proliferation was a more important factor related with hepatoma relapse, except the reason that extrusion during operation lead hepatoma ceils moved to other place. Conclusion To decrease body emergency reaction after operation damage may be very important to prevent hepatoma relapse rate or to prolong relapse time.