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阿奇霉素治疗新生儿沙眼衣原体肺炎疗效观察
引用本文:陈贻骥,周有碧,吴仕孝. 阿奇霉素治疗新生儿沙眼衣原体肺炎疗效观察[J]. 中华儿科杂志, 1999, 37(7): 418-419
作者姓名:陈贻骥  周有碧  吴仕孝
作者单位:重庆医科大学附属儿童医院新生儿科
摘    要:目的 探讨阿奇霉素治疗新生儿沙眼衣原体肺炎的疗效。方法 15例Ct肺炎用阿奇霉素治疗,10mg/(kg.d),每天1次连用3天,其鼻咽拭子标本用McCoy细胞培养,结果 所有病例用药后5-7天症状明显改善。3例治疗后8天重复Ct培养转阴。未发现明显胃肠道副作用,较使用红霉素等药物,疗程明显缩短,且副作用少。

关 键 词:叠氮红霉素 衣原体 肺炎 新生儿 治疗

The effect of azithromycin on the treatment of neonatal Chlamydia trachomatis pneumonia
CHEN Yiji,ZHOU Youbi,WU Shixiao,et al Childrens Hospital,Chongqing Medical University,Chongqing. The effect of azithromycin on the treatment of neonatal Chlamydia trachomatis pneumonia[J]. Chinese journal of pediatrics, 1999, 37(7): 418-419
Authors:CHEN Yiji  ZHOU Youbi  WU Shixiao  et al Childrens Hospital  Chongqing Medical University  Chongqing
Affiliation:CHEN Yiji,ZHOU Youbi,WU Shixiao,et al Childrens Hospital,Chongqing Medical University,Chongqing 400014
Abstract:Objective To investigate the effect of azithromycin on treating neonatal pneumonia caused by chlamydia trachomatis (Ct) Methods Fifteen cases of neonatal pneumonia with positive Ct in nasopharyngeal cultures were treated with azithromycin at a dose of 10 mg/(kgd) for 3 days. Nasopharyngeal swabs of these patients were taken for the isolation of Ct in McCoy cell cultures Results Symptoms of all patients were improved 57 days after azithromycin treatment The Ct cultures became negative in 3 patients 8 days after therapy No obvious gastrointestinal sideeffects were observed The course of azithromycin treatment was much shorter than that of erythromycin treatment and showed a few sideeffects. Conclusion Azithromycin is effective in treating neonatal pneumonia caused by Ct Neonates presented good tolerance for the treatment with azithromycin
Keywords:AzithromycinChlamydia trachomatisChlamydia pneumoniaInfant  newborn
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