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| 长期肠外营养与胆汁淤积症相关因素的临床分析 | |
| 引用本文： | 乔立兴,郑意楠,钱钻好,黄莉,毕明远,李海浪. 长期肠外营养与胆汁淤积症相关因素的临床分析[J]. 肠外与肠内营养, 2008, 15(1): 36-38 |
| 作者姓名： | 乔立兴 郑意楠 钱钻好 黄莉 毕明远 李海浪 |
| 作者单位： | 东南大学附属中大医院儿科,江苏南京,210009 |
| 摘 要： | 目的:分析危重症新生儿肠外营养(PN)相关性胆汁淤积症(PNAC)的临床特点及影响因素,探讨其预后.方法:在我院接受PN治疗时间超过2周的婴儿64例,其中发生PNAC 15例(PNAC组)和未发生PNAC(对照组)49例.所有病儿均明确原基础疾病治疗恢复情况以及PN实施情况,特别是在PN期间有无肠道喂养以及何时开始喂养等,计算每天PN补充热量及各种营养成分.对发生胆汁淤积症病儿均进行常规保肝、利胆治疗2～4周,期间每周监测血生化、肝功能,并监测经皮胆红素.治疗结束后根据情况每2～4周复查肝功能和血生化及肝B超.所有病儿均随访至6个月.结果:①本组PNAC总发生率为23.4%.PNAC组中,体质量＜2000g者占80.0%;而对照组中占42.9%,两组比较有显著性差异(P＜0.05).②PN第1周内完全禁食者,PNAC组为80.0%,对照组为22.4%,两组比较有显著性差异(P＜0.05).③PNAC组中预后良好者为73.3%,而对照组为95.9%,两组比较有显著性差异(P＜0.05).结论:新生儿长期PN相关性胆汁淤积症的发生与否,与病儿出生时体质量、PN过程中是否尽早进行胃肠内营养密切相关. |
| 关 键 词： | 新生儿 肠外营养 胆汁淤积 |
| 文章编号： | 1007-810X(2008)01-0036-03 |
| 修稿时间： | 2007-04-12 |
Relationship between long-term parenteral alimentation and the cholestasis |
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| QIAO Li-xing,ZHENG Yi-nan,QIAN Zuan-hao,HUANG Li,BI Ming-yuan,LI Hai-lang. Relationship between long-term parenteral alimentation and the cholestasis[J]. Parenteral & Enteral Nutrition, 2008, 15(1): 36-38 | |
| Authors: | QIAO Li-xing ZHENG Yi-nan QIAN Zuan-hao HUANG Li BI Ming-yuan LI Hai-lang |
| Affiliation: | QIAO Li-xing,ZHENG Yi-nan,QIAN Zuan-hao,HUANG Li,BI Ming-yuan,LI Hai-lang(Department of Pediatrics,the Affiliated Zhongda Hospital,Southeast University,Nanjing 210009,Jiangsu,China) |
| Abstract: | Objective:To analyze the clinical features and influential factors of parenteral nutrition associated cholestasis(PNAC) in high-risk neonate.Methods:64 newborns admitted to the neonatal intensive care unit during 2002.1~2004.10 were divided into the PNAC group(15) and the control group(49).All of the 64 neonates were supported with parenteral nutrition more than 2 weeks and followed up for 6 months.The birth weight,gestation age,disease,nutrition intake(time,amount,kinds,means,etc) and treatment were record... |
| Keywords: | Neonate Parenteral Alimentation cholestasis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |