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异体骨髓基质细胞促进引导性骨再生的实验研究
引用本文:谢江涛,陈廖斌. 异体骨髓基质细胞促进引导性骨再生的实验研究[J]. 武汉大学学报(医学版), 2011, 32(5): 600-603
作者姓名:谢江涛  陈廖斌
作者单位:武汉大学中南医院骨科 湖北武汉430071
摘    要:目的:利用膜引导组织再生技术,将复合异体骨髓基质细胞(BMSCs)的明胶海棉移植于硅胶膜管内,旨在观察异体BMSCs促进膜引导骨组织再生的能力.方法:抽取大耳白兔胫骨结节及股骨转子处骨髓,经密度梯度离心,贴壁筛选,获取BMSCs并培养、扩增.36只成年新两兰兔随机分成3组,每组12只,造成双侧12 mm桡骨缺损,A组缺...

关 键 词:骨髓基质细胞  移植  引导性骨再生  骨缺损  修复

Experimental Study on Stimulation of Guided Bone Regeneration by Allogeneic Bone Marrow Stromal Cells
XIE Jiangtao,CHEN Liaobin. Experimental Study on Stimulation of Guided Bone Regeneration by Allogeneic Bone Marrow Stromal Cells[J]. Medical Journal of Wuhan University, 2011, 32(5): 600-603
Authors:XIE Jiangtao  CHEN Liaobin
Affiliation:XIE Jiangtao,CHEN Liaobin Dept.of Orthopaedics,Zhongnan Hospital of Wuhan University,Wuhan 430071,China
Abstract:Objective:To investigate whether allogeneic bone marrow stromal cells would facilitate bone healing combined with guided bone regeneration(GBR).Methods:Bone marrow stromal cells were obtained from tibial tuberosity and femur greater trochanter of New Zealand rabbits.A 12 mm long segmental defect was created in the diaphyses of both radii of rabbits.The defect was bridged with a silicon tube.The group A were instilled with allogeneic bone marrow stromal cells into the tube,group B were instilled with autolog...
Keywords:Bone Marrow Stromal Cells  Transplantation  Guided Bone Regeneration  Bone Defect Reparation  
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