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造血系统恶性肿瘤外周血干细胞分离冻存及其临床应用
引用本文:谢晓宝 华铮. 造血系统恶性肿瘤外周血干细胞分离冻存及其临床应用[J]. 临床血液学杂志, 1996, 9(2): 50-52
作者姓名:谢晓宝 华铮
作者单位:江苏省常州市第一人民医院
摘    要:
报告应用Haemonetics V50 PLUS血细胞分离机对4种造血系统恶性肿瘤病人进行外周血干细胞采集,冻存的结果,第1次完全缓解早期4例病 均能收集到足够的外周血干细胞量进行自体移植,1例病人静脉应用动员剂GM-CSF能提高外周血干细胞的采集效率,初步观察到化疗药物的累积损害对外周血干细胞的采集有不利影响。

关 键 词:肿瘤 造血系统 APSCT

Stem Cells and It''''s Application in Hematopoietic Isolation and Cryopreservation of Peripheral Blood in Malignancies
XIe xiaohao,Qou Guoqiang,Cheng Yekuan et al. Stem Cells and It''''s Application in Hematopoietic Isolation and Cryopreservation of Peripheral Blood in Malignancies[J]. Journal of Clinical Hematology, 1996, 9(2): 50-52
Authors:XIe xiaohao  Qou Guoqiang  Cheng Yekuan et al
Abstract:
In this paper we reported the results of isolation and cryopreservation of peripheral blood stem cells and it's application in hematopoietic malignancies.Suffcient peripheral blood stem cells could be obtained from four patients during the first complete remission for trans plantation,GM-CSF infusion in one patient significantly mobilized the peripheral blood stem cells.The degree of chemotherapy had hamfull effect on collect of the stem cells.In our study,the effect of the cell concentration during cryopreservation on the recovery of GM-CFU was not observed.
Keywords:Hematopoietic malignancy Peripheral blood stem cell
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