Benzamil prevents brain water accumulation in hyponatraemic rats |
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| Authors: | Endre Sulyok József Pál Zsolt Vajda Roy Steier Tamás Dóczi |
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| Institution: | 1.Institute of Health Promotion and Family Care, Faculty of Health Sciences,University of Pécs,Pécs,Hungary;2.Department of Neurosurgery, Faculty of Medicine,University of Pécs,Pécs,Hungary;3.Department of Neuroimaging, Center of Health Sciences,University of Kaposvár,Kaposvár,Hungary |
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| Abstract: | Background It has been recently shown that A6 cells exposed to hyponatraemic stress respond with increased sodium uptake via activation
of benzamil-sensitive sodium channels. This study was performed, therefore, to explore the possible involvement of benzamil-sensitive
sodium channels and cellular sodium influx in brain oedema formation in hyponatraemic rats. |
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