101例大肠癌术后肝转移治疗分析

目的比较大肠癌肝转移患者不同治疗方法的疗效。材料与方法将１０１例原发灶得到控制，无肝外播散的大肠癌肝转移患者按治疗方法不同分为３组，其中手术切除＋肝动脉化疗组４０例，动脉插管化疗＋放疗组３４例，静脉化疗组２７例。结果手术切除＋动脉化疗组１，３，５年生存率分别为６７．５％，５０．０％，２７．５％，明显高于其他两治疗组，Ｐ值均小于０．０５。动脉化疗＋放疗组的治疗有效率１，３年生存率分别高于静脉化疗组，Ｐ值均小于０．０５。结论对原发灶得到控制，无肝外播散的大肠癌肝转移患者应争取切除孤立或仅局限于一叶的多发病灶；对不可切除的病例选用动脉化疗辅助放疗不失为一重要的治疗手段。

Treatment for Iiver metastases for patients with colorectal carcinoma after surgery-analysis of 101 cases

Purpose To investigate the clinical effect of various treatment methods on colorectal carcinoma patients with liver metastases after surgery. Materials and Methods 101 patients were divided into three groups,40 patients received surgery plus arterial infusion chemotherapy,34 patients were treated by arterial infusion chemotherapy plus radiotherapy and 27 patients by system chemotherapy .Results The results showed that 1,3 and 5 year survival rates of surgery plus arterial chemotherapy group were 67.5%,50.0% and 27.5% which were better than the other two non-surgery group(P<0.05).The 1,3 year survival rates of artery chemotherapy plus radiotherapy plus radiotherapy group were better than that of system chemotherapy group(P<0.05)Conclusion We suggest that the resection be performed for single or multiple tumors in one lobe when the primary tumor be controlled by surery without extrahepatic metastases For unresectable patients ,it is advised to perform arterial infusion with radiotherapy.