| 小细胞肺癌内科治疗新进展 |
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| 引用本文： | 阿丽亚·奥斯曼,王效刚,刘俊远,帕提古力·阿尔西丁.小细胞肺癌内科治疗新进展[J].现代肿瘤医学,2023,0(7):1362-1366. |
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| 作者姓名： | 阿丽亚·奥斯曼 王效刚 刘俊远 帕提古力·阿尔西丁 |
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| 作者单位： | 1.新疆医科大学第三临床医学院（新疆医科大学附属肿瘤医院）,新疆 乌鲁木齐 830011；2.新疆医科大学第三临床医学院（新疆医科大学附属肿瘤医院）肺内科一病区，新疆 乌鲁木齐 830011 |
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| 基金项目： | 新疆维吾尔自治区自然科学基金(编号:2022D01C294) |
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| 摘 要： | 小细胞肺癌（small cell lung cancer，SCLC）具有极高的增殖率、较强的早期转移倾向和较差的预后。超过三分之二的患者初诊时分期为广泛期（extensive stage-small cell lung cancer，ES-SCLC）。小细胞肺癌治疗进展缓慢，含铂化疗一直是标准治疗方案，虽然近期有效率高，但易出现耐药。近年来免疫治疗及抗血管药物的兴起，在SCLC领域出现了突破，为SCLC建立新的治疗标准。本文将SCLC的化学治疗、抗血管治疗及免疫治疗进展进行综述。
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| 关 键 词： | 小细胞肺癌 化疗 耐药 抗血管治疗 免疫治疗 |
Advances in the internal medicine treatment of small cell lung cancer |
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| Aliya Aosiman,WANG Xiaogang,LIU Junyuan,Patiguli Aerxiding.Advances in the internal medicine treatment of small cell lung cancer[J].Journal of Modern Oncology,2023,0(7):1362-1366. |
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| Authors: | Aliya Aosiman WANG Xiaogang LIU Junyuan Patiguli Aerxiding |
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| Institution: | 1.The Third Clinical Medical College of Xinjiang Medical University,Tumor Hospital Affiliated to Xinjiang Medical University,Xinjiang Urumqi 830011,China;2.Department of Thoracic Oncology,the Third Clinical Medical College of Xinjiang Medical University,Tumor Hospital Affiliated to Xinjiang Medical University,Xinjiang Urumqi 830011,China. |
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| Abstract: | Small cell lung cancer(SCLC) has a very high proliferation rate,a strong tendency to metastasise early and a poor prognosis.More than two-thirds of patients are initially diagnosed with extensive stage(ES-SCLC).Treatment of small cell lung cancer has progressed slowly and platinum-containing chemotherapy has been the standard of care,which,although recently highly effective,is prone to drug resistance.The rise of immunotherapy and anti-vascular agents in recent years has led to breakthroughs in the field of SCLC,establishing a new standard of care for SCLC.This article reviews advances in chemotherapy,anti-vascular therapy and immunotherapy for SCLC. |
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| Keywords: | small cell lung cancer(SCLC) chemotherapy drug resistant anti-vascular therapy immunotherapy |
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