| 儿童肾病综合征病理类型与年龄、性别的关系 |
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| 引用本文： | 任献国,刘光陵,夏正坤,高远赋,樊忠民,何旭,茅松.儿童肾病综合征病理类型与年龄、性别的关系[J].临床儿科杂志,2011,29(8). |
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| 作者姓名： | 任献国 刘光陵 夏正坤 高远赋 樊忠民 何旭 茅松 |
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| 作者单位： | 1. 南京中医药大学,江苏南京,210046;南京军区南京总医院儿科,江苏南京,210003
2. 南京军区南京总医院儿科,江苏南京,210003 |
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| 摘 要： | 目的 探讨肾病综合征患儿的肾脏病理和性别、年龄分期的关系.方法 对1 116例经肾穿刺活检明确肾脏病理的原发性肾病综合征患儿临床资料进行回顾性分析.结果 1 116例患儿中男817例,女299例,男女比例2.73:1;平均年龄(7.3 ± 3.3)岁,其中婴幼儿期90例,学龄前期294例,学龄期409例,青春期323例.肾脏病理轻微病变(MCNS)222例,占19.9%;系膜增生性肾小球肾炎(MsPGN)726例,占65.1%;膜增生性肾小球肾炎(MPGN)55例,占4.9%;膜性肾小球肾炎(MN)27例,占2.4%;局灶节段硬化性肾小球肾炎(FSGS)86例,占7.7%.肾脏病理类型在4个年龄分期的分布差异有统计学意义,MCNS患儿以学龄前期最多,MsPGN患儿以学龄期最多,MPGN和MN患儿以青春期最多,FSGS的患儿以学龄期最多.MCNS患儿的男女比例为5.3:1,MsPGN为2.4:1,MPGN为0.96:1,MN为3.5:1,FSGS为2.7:1,肾脏病理类型在性别上的分布差异有统计学意义(P ＜ 0.05).结论 对于无法开展肾活检的医院或有肾穿刺禁忌证的患儿,可根据年龄和性别结合临床检验初步推断肾脏病理变化的轻重,进一步指导治疗、判断预后.
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| 关 键 词： | 肾病综合征 病理 年龄 性别 儿童 |
Age and geader in pathological typing of 1116 children with nephrotic syndrome |
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| REN Xian-guo,LIU Guang-ling,XIA Zheng-kun,GAO Yuan-fu,FAN Zhong-min,HE Xu,MAO Song.Age and geader in pathological typing of 1116 children with nephrotic syndrome[J].The Journal of Clinical Pediatrics,2011,29(8). |
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| Authors: | REN Xian-guo LIU Guang-ling XIA Zheng-kun GAO Yuan-fu FAN Zhong-min HE Xu MAO Song |
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| Institution: | REN Xian-guo1,2,LIU Guang-ling2,XIA Zheng-kun2,GAO Yuan-fu2,FAN Zhong-min2,HE Xu2,MAO Song2(1.Nanjing University of Chinese Medicine,Nanjing 210046,Jiangsu,China,2.Department of Pediatrics,Nanjing General Hospital of Nanjing Military Command,Nanjing 210003,China) |
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| Abstract: | Objective Renal pathological types of 1 116 children suffering from primary nephrotic syndrome from March 1992 to March 2010 in Nanjing General Hospital of Nanjing Military Command were reviewed.Relationship between renal pathology and age or gender in these children was analyzed.Methods Renopuncture was performed to 1 116 children with primary nephrotic syndrome to identify pathological types.According to the age,those children were divided into four groups:infancy,pre-school age,school age and adolescence... |
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| Keywords: | nephrotic syndrome pathology age gender children |
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