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| 丹参素脂质体的制备研究 | |
| 引用本文： | 曾昭武,王小丽. 丹参素脂质体的制备研究[J]. 中医药导报, 2008, 14(8) |
| 作者姓名： | 曾昭武 王小丽 |
| 作者单位： | 中南大学生物医学工程研究院,湖南长沙,410008;江西宜春学院,江西宜春,336000 |
| 摘 要： | 目的:研究丹参素脂质体的处方、制备工艺.方法:以脂质体的包封率为指标评价,采用正交设计对制备工艺进行优化,用反相蒸发超声法制得丹参素脂质体.结果:成功制得丹参素脂质体,其平均粒径为75.4 nm,丹参素脂质体的平均包封率为55.23%.结论:丹参素脂质体制备方法简单可行. |
| 关 键 词： | 丹参素=脂质体 制备工艺 |
Study of Preparation of Tanshinol Liposomes |
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| ZENG Zhao-wu,WANG Xiao-li. Study of Preparation of Tanshinol Liposomes[J]. GUIDING JOURNAL OF TCM, 2008, 14(8) | |
| Authors: | ZENG Zhao-wu WANG Xiao-li |
| Abstract: | Objective: To study the formula,preparation of Tanshinol liposomes.Methods: The enbedding ratio as an index was evaluated to the optimizing preparation technology with an orthogonal design.Tegafur common liposome was prepared with reverse phase evaporation and supersound method.Results: Tanshinol liposomes were prepared successfully with 75.4 nm mean diameter and 55.23% mean enbedding ratio.Conclusion: Tanshinol liposome with a simple preparation condition. |
| Keywords: | Tanshinol liposomes |
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