| 2型糖尿病大血管病变患者血清胰岛素样因子-1水平变化及其临床意义 |
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| 引用本文： | 潘优津,赵向彤,吴朝明,陈俐丽. 2型糖尿病大血管病变患者血清胰岛素样因子-1水平变化及其临床意义[J]. 中国慢性病预防与控制, 2007, 15(2): 140-141 |
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| 作者姓名： | 潘优津 赵向彤 吴朝明 陈俐丽 |
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| 作者单位： | 1. 温州医学院附属二院,内分泌科,浙江,温州,325000
2. 温州医学院附属二院,检验科,浙江,温州,325000 |
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| 摘 要： | 目的研究2型糖尿病大血管病变患者血清胰岛素样生长因子-1(IGF-1)水平变化及其临床意义。方法正常对照组30例,2型糖尿病无合并症组27例,2型糖尿病合并大血管病变组30例,用酶联免疫吸附法分别测定各组血清IGF-1水平。结果对照组IGF-1(186.79±79.35)pg/ml,2型糖尿病无合并症组IGF-1(91.78±24.00)pg/ml,与对照组相比明显降低,差别有统计学意义(P<0.01);2型糖尿病合并大血管病变组IGF-1(65.73±12.54)pg/ml,较2型糖尿病无合并症组降低,差别有统计学意义(P<0.01)。结论2型糖尿病无合并症者血清IGF-1水平降低,2型糖尿病合并大血管病变者血清IGF-1水平更低,其在大血管病变的发生、发展中起重要作用。
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| 关 键 词： | 糖尿病,2型 糖尿病血管病变 胰岛素样生长因子-1 |
| 文章编号： | 1004-6194（2007）02-0140-02 |
| 收稿时间： | 2006-10-08 |
| 修稿时间： | 2006-11-17 |
The Relationship between Type 2 Diabetic Macroangiopathy and the Levels of Serum Insulin-like Growth Factor-1 |
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| PAN You-jin,ZHAO Xiang-tong,WU Chao-ming,et al.. The Relationship between Type 2 Diabetic Macroangiopathy and the Levels of Serum Insulin-like Growth Factor-1[J]. Chinese Journal of Prevention and Control of Chronic Non-Communicable Diseases, 2007, 15(2): 140-141 |
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| Authors: | PAN You-jin ZHAO Xiang-tong WU Chao-ming et al. |
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| Affiliation: | PAN You-jin,ZHAO Xiang-tong,WU Chao-ming,et al.Department of Endocrinology,The Second Hospital of Wenzhou Medical College,Zhejiang 325000,China |
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| Abstract: | Objective To investigate the relationship between insulin-like growth factor-1(IGF-1)and type 2 diabetic macroangiopathy.Methods The serum IGF-1 was detected by ELISA in 30 of healthy controls,30 of type 2 diabetes without complications and 30 of type 2 diabetic macroangiopathy patients.Results The serum IGF-1 in type 2 diabetes was lower than that in healthy controls(P<0.01);The serum IGF-1 in type 2 diabetic macroangiopathy was obviously lower than that in type 2 diabetes without complications(P<0.01).Conclusion IGF-1 may play an important role in the development and progression of type 2 diabetic macroangiopathy. |
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| Keywords: | Diabetes Macroangiopathy Insulin-like growth factor-1 |
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