| 复方镇痛膏对小鼠镇痛镇定作用的初步研究 |
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| 引用本文： | 黄如栋,薛团梅,车苏容,苏晓宇,林善春.复方镇痛膏对小鼠镇痛镇定作用的初步研究[J].福建中医学院学报,2001,11(4):32-34. |
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| 作者姓名： | 黄如栋 薛团梅 车苏容 苏晓宇 林善春 |
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| 作者单位： | 1. 福建中医学院药学系,福建,福州,350003
2. 福安市医药有限公司,福建,福安,355000 |
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| 基金项目： | 福建省教育厅资助课题 ( JA992 0 4) |
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| 摘 要： | 采用热板法和醋酸扭体法观察了复方镇痛膏对小鼠的镇痛作用，采用尾悬挂法和协同阈下剂量水合氯醛催眠的方法观察了对小鼠的镇定作用。结果发现该药明显减少醋酸所致小鼠的扭体次数，小幅提高小鼠对热刺激的痛阈，显著延长悬挂小鼠的不动时间，显著提高阈下剂量水合氯醛致小鼠的睡眠率。证明复方镇痛膏具有显著的镇痛镇定作用。
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| 关 键 词： | 复方镇痛膏 镇定 镇痛 小鼠 中药 |
| 文章编号： | 1004-5627(2001)04-0032-03 |
| 修稿时间： | 2001年8月16日 |
Study of Compound Sedative Paste On Analgesic and Sedative Effects |
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| HUANG Ru dong\,XUE Tuan mei\,CHE Su rong\,et al\.Study of Compound Sedative Paste On Analgesic and Sedative Effects[J].Journal of Fujian College of Traditional Chinese Medicine,2001,11(4):32-34. |
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| Authors: | HUANG Ru dong\ XUE Tuan mei\ CHE Su rong\ et al\ |
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| Institution: | HUANG Ru dong\+1,XUE Tuan mei\+2,CHE Su rong\+1,et al\, |
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| Abstract: | The analgesic effects of compound sedative paste were observed by hot plate and acetic acid inducing writhing models,and the sedative effects were observed by testing the stillness time of tail suspension mice in 6 seconds and noting the number of sleep mice induced by subthreshold doses of choral hydrate.The results showed that the paste could obviously decrease the writhing times,increase the pain threshold for thermal stimulation a little,prolong stillness time of tail suspension mice,and increase the number of sleep mice induced by subthreshold doses of choral hydrate.It indicates that the paste has the analgesic and sedative effects. |
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| Keywords: | compoud sedative paste sedation analgetic mice |
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