| 桃仁不同提取物抗血栓作用的实验研究 |
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| 引用本文： | 汪宁,刘青云,彭代银,王兰,王胜祥.桃仁不同提取物抗血栓作用的实验研究[J].中药材,2002,25(6):414-415. |
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| 作者姓名： | 汪宁 刘青云 彭代银 王兰 王胜祥 |
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| 作者单位： | 安徽中医学院药学系,合肥230038 |
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| 摘 要： | 目的：比较桃仁不同提取物抗血栓作用，为寻找确定其抗血栓作用有效部位提供实验依据。方法：制备桃仁不同提取物，观察其小鼠凝血时间、ADP诱导的小鼠肺血栓状态及电刺激大鼠颈总动脉血栓形成的影响。结果：桃仁的乙酸乙酯提取物能延长小鼠的凝血时间、缓解ADP诱导的小鼠肺栓塞所致的呼吸窘迫症状，能明显延长实验性大鼠血栓形成的时间。结论：桃仁乙酸乙酯的提取物有显著的抗血栓作用。
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| 关 键 词： | 桃仁 提取物 乙酸乙酯 抗血栓作用 实验研究 |
| 修稿时间： | 2001年12月25 |
Experimental Study on Anfi-thrombus Effect of Different Extracts from Semen Persicae |
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| Wang Ning,Liu Qingyun,Peng Daiyin,Wang Lan,Wang Shengxiang.Experimental Study on Anfi-thrombus Effect of Different Extracts from Semen Persicae[J].Jorunal of Chinese Medicinal Materials,2002,25(6):414-415. |
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| Authors: | Wang Ning Liu Qingyun Peng Daiyin Wang Lan Wang Shengxiang |
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| Institution: | Department of Pharmacy, Anhui College of Traditional Chinese Medicine, Heifei 2300038. |
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| Abstract: | Objective: To observe the effects of anti-thrombus of different extracts from Semen Persicae and provide experimental basis for finding and defining effective fraction of Semen Persicae. Methods:The effects of different extracts from Semen Persicae on clotting time in mice, pulmonary embolism in mice and electro-irritate thrombosis in rats were observed. Result:Ethyl acetate extract fron Semen Persicae could prolong clotting time in mice, markedly relieve respiratory difficult due to pulmonary embolism in mice induced by ADP-Na, obviously retard the generation of thrombosis induced by electrical injury of carotid artery in rats. Conclusion: Ethyl acetate extract from Semen Persicae possesses evidently anti-thrombotic effect. |
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| Keywords: | Semen Persicae Extracts Ethyl acetate Anti-thrombus |
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