| 免疫抑制剂咪唑立宾的药理作用及临床应用 |
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| 引用本文： | 董亚琳,董海燕.免疫抑制剂咪唑立宾的药理作用及临床应用[J].中国新药杂志,2005,14(7):930-932. |
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| 作者姓名： | 董亚琳 董海燕 |
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| 作者单位： | 西安交通大学医学院第一附属医院临床药学室,西安,710061 |
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| 摘 要： | 通过文献检索综述了免疫抑制剂咪唑立宾的药理作用、药动学、临床应用和不良反应.咪唑立宾可作为免疫抑制剂硫唑嘌呤的替代品用于肾移植、肾病综合征、类风湿性关节炎和系统性红斑狼疮.
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| 关 键 词： | 咪唑立宾 免疫抑制剂 药理作用 临床应用 |
| 文章编号： | 1003-3734（2005）07-0930-03 |
| 修稿时间： | 2005-04-12 |
Pharmacological action and clinical use of mizoribine |
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| DONG Ya-lin,DONG Hai-yan.Pharmacological action and clinical use of mizoribine[J].Chinese Journal of New Drugs,2005,14(7):930-932. |
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| Authors: | DONG Ya-lin DONG Hai-yan |
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| Abstract: | Mizoribine, a derivative of mycophenolic acid, has demonstrated the potential for the use of this drug as a substitute of an immunosuppressive agent azathioprine for the rejection of organ grafts transplant, renal syndromes and systemic lupus erythematosus. This paper reviews the pharmacological mechanism, pharmacokinetics, pharmacotherapy and safety profile of mizoribine. |
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| Keywords: | mizoribine immunosuppressant pharmacological action clinical use |
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