| 蛇床子挥发油GC和GC-MS指纹图谱的研究 |
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| 引用本文： | 赵陆华,单臻,李晓晶,相秉仁.蛇床子挥发油GC和GC-MS指纹图谱的研究[J].中国药学杂志,2007,42(12):889-891. |
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| 作者姓名： | 赵陆华 单臻 李晓晶 相秉仁 |
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| 作者单位： | 药物质量与安全预警教育部重点实验室;分析测试中心,中国药科大学,南京,210009 |
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| 摘 要： | 目的采用GC和GC-MS色谱法研究并建立各产地蛇床子药材挥发油成分的指纹图谱。方法用DB-5石英毛细管柱(0.25 mm×30 m,0.25μm);以高纯氮为载气;流速1.0 mL·min-1;FID检测器。结果蛇床子药材指纹图谱选定了10个共有峰,峰面积之和大于总峰面积的90%,并且通过质谱进行了鉴别。结论本法重现性好,可结合蛇床子药材的HPLC指纹图谱评价其质量。
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| 关 键 词： | 蛇床子药材 挥发油 指纹图谱 气相色谱 气相色谱-质谱 |
| 文章编号： | 1001-2494（2007）12-0889-03 |
| 收稿时间： | 2006-04-30; |
| 修稿时间： | 2006-04-31 |
Studies on Fingerprints of Fructus cnidii by GC and GC-MS |
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| ZHAO Lu-hua,SHAN Zhen,LI Xiao-jing,XIANG Bing-ren.Studies on Fingerprints of Fructus cnidii by GC and GC-MS[J].Chinese Pharmaceutical Journal,2007,42(12):889-891. |
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| Authors: | ZHAO Lu-hua SHAN Zhen LI Xiao-jing XIANG Bing-ren |
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| Institution: | 1. Drug Quality Control and Pharmacovilance Ministry of Education ;2. Center for Instrumental Analysis , China Pharmaceutical University, Nanfing 210009, China |
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| Abstract: | OBJECTIVE To study the fingerprints of different Fructus cnidii samples by GC and GC-MS.METHODS The separation was performed on a DB-5(0.25 mm×30 m,0.25 μm) column with the flow rate of 1.0 mL·min-1.The carrier gas was nitrocen gas.The contents were determined by FID.RESULTS 10 Common peaks were obtained in the GC fingerprints of Fructus cnidii volatile oil and they were identified by GC-MS.CONCLUSION The method has good repeatability.This GC fingerprint combined with the HPLC fingerprint of Fructus cnidii can be used to evaluate its quality integrally. |
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| Keywords: | Fructus cnidii volatile oil fingerprint GC GC-MS |
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