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Fractional CO2 laser: a novel therapeutic device for refractory necrobiosis lipoidica
Authors:Gionata Buggiani  Dionigi Tsampau  Alena Krysenka  Vincenzo De Giorgi  Jana Hercogová
Affiliation:1. Private Practitioner of Dermatology and Venereology, , Florence, Italy;2. Azienda Sanitaria Firenze, , Florence, Italy;3. University of Florence School of Medicine, , Florence, Italy;4. Dermatology Department, 2nd Medical Faculty, Charles University, , Prague, Czech Republic
Abstract:
Necrobiosis lipoidica diabeticorum is a granulomatous skin disease of uncertain pathogenesis. Many therapeutic approaches have been reported in the literature, but none of them can be considered the gold standard. Fractional CO2 laser treatment shows peculiar effects in the skin, mainly due to its ability of modulating cytokine pathways of tissue‐repairing mechanisms. Thus, we propose fractional CO2 laser in the management of refractory necrobiosis lipoidica in selected recalcitrant patients.
Keywords:CO2 laser  necrobiosis lipoidica  fractional
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