| 抗心绞痛药的药物相互作用 |
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| 引用本文： | 李筱旻,郭歆,程泽能. 抗心绞痛药的药物相互作用[J]. 中国临床药理学与治疗学, 2007, 12(5): 493-498 |
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| 作者姓名： | 李筱旻 郭歆 程泽能 |
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| 作者单位： | 中南大学药学院药物代谢与药物动力学研究所,长沙,410013,湖南 |
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| 摘 要： | 心绞痛是常见的心血管疾病。临床常用的抗心绞痛药易发生药物之间的相互作用。本文综述了与常用抗心绞痛药物相关的药动学方面的相互作用研究进展,为临床用药提供参考。
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| 关 键 词： | 抗心绞痛药物 药物相互作用 药动学 细胞色素P450 |
| 文章编号： | 1009-2501（2007）05-0493-06 |
| 修稿时间： | 2007-03-122007-05-09 |
Drug interactions with antianginal drugs |
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| LI Xiao-min,GUO Xin,CHENG Ze-neng. Drug interactions with antianginal drugs[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2007, 12(5): 493-498 |
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| Authors: | LI Xiao-min GUO Xin CHENG Ze-neng |
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| Affiliation: | Research Institute of Drug Metabolism and Pharmacokinetics, School of Pharmaceutical Sciences, Central South University, Changsha 410013, Hunan, China |
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| Abstract: | Angina pectoris is the major clinical symptom of myocardial ischemia. Angina pectoris can be managed by using drugs that either improve perfusion of the myocardium or reduce its metabolic demand. Many of the drugs used in angina pectoris are the substrate of cytochrome P450, drug interactions are easily to occur when antianginal drugs co-administrated with other drugs and foods. In this article, the drug interaction of main antianginal drugs in pharmacokinetics were reviewed, and it will help the rational use of antianginal drugs in clinical medication. |
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| Keywords: | antianginal drugs drug interaction pharmacokinetics cytochrome P450 |
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