反向被动血凝抑制法用于流行性出血热血清抗体分型的试验

本文报告了用反向被动血凝抑制(RPHI)法进行流行性出血热血清抗体分型的实验结果。用该法共检查福建以EHF野鼠型为主和家鼠型疫区患者恢复期病人血清58份,发现前者A型34份(94.44%),后者R型22份(100%),证明了RPHI法与HI法对EHF血清抗体分型的结果是一致的。证实RPHI在临床诊断上的敏感性与特异性,可用于该病的血清抗体分型并具有实用价值。该病用本法进行抗体分型,国内外尚未见报道。

Differentiation of the Type of EHF Antibodies by RPHI

This article reports the use of for differentiation of the type of EHF antibodies. A total of 58 convalescent-phase sera from EHF patients in natural foci of predominant Apodemus type of EHF and in those of Rattus type of EFH were examined. In the former 34/36 (94.44%) belonged to Apodemus type, and in the latter 22/22 (100%) belonged to Rattus type. Both RPHI and HI obtained the same result in differentiation of the type of EHF antibodies. RPHI possesses sensitivity and specificity in EHF diagnosis, and may be used for differentiation of the type of EHF antibodies.