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噻托溴铵联合福莫特罗吸入治疗慢性阻塞性肺疾病
引用本文:林琳,赵立. 噻托溴铵联合福莫特罗吸入治疗慢性阻塞性肺疾病[J]. 实用药物与临床, 2009, 12(3)
作者姓名:林琳  赵立
作者单位:中国医科大学附属盛京医院呼吸内科,沈阳,110004
摘    要:
目的观察噻托溴铵联合福莫特罗吸入治疗慢性阻塞性肺疾病(COPD)的效果及安全性。方法46例COPD患者随机分为2组,对照组23例,常规给予福莫特罗治疗;治疗组23例,噻托溴铵联合福莫特罗吸入治疗,疗程4周。观察治疗前、后的临床症状及肺功能变化。结果治疗组对FEV1的改善显著高于对照组(P<0.05)。治疗组减轻日常症状的效果优于对照组。各组均未出现明显不良反应。结论吸入噻托溴铵与福莫特罗联合治疗COPD,疗效优于单药治疗。

关 键 词:慢性阻塞性肺疾病  噻托溴铵  福莫特罗

Effect of tiotropium bromide inhalation combined with formoterol inhalation on chronic obstructive pulmonary disease
LIN Lin,ZHAO Li. Effect of tiotropium bromide inhalation combined with formoterol inhalation on chronic obstructive pulmonary disease[J]. Practical Pharmacy and Clinical Remedies, 2009, 12(3)
Authors:LIN Lin  ZHAO Li
Abstract:
Objective To study the effect and safety of tiotropium bromide inhalation combined with formoterol inhalation on chronic obstructive pulmonary disease(COPD).Methods46 COPD patients were randomly divided into 2 groups.Treatment group was treated with tiotropium bromide + formoterol;control group was treated with formoterol.The course was 4 weeks.The symptoms and lung function were observed before and after treatment.ResultsThere were significant differences in the symptoms and FEV1 between 2 groups(P<0.05).No significant adverse reaction was found.ConclusionThe therapeutic effect of tiotropium bromide inhalation and formoterol inhalation on COPD is better than that of tiotropium.
Keywords:Chronic obstructive pulmonary disease(COPD)  Tiotropium bromide  Formoterol
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