Nucleus24型人工耳蜗使用者电诱发听神经复合动作电位的测定

目的 :探讨电诱发听神经复合动作电位 (ECAP)的特点及在人工耳蜗临床中的应用价值和意义。方法 :应用NRT(neuralresponsetelemetry)软件 ,通过体外言语处理器和耳蜗内的植入电极系统 ,采用单极模式电极刺激和近场记录方法 ,对 37例NucleusCI2 4M装置使用者进行ECAP的记录。对其中 12例使用者做了行为测试。结果 :87.6 %的使用者记录到ECAP波形。分析了有行为阈值的 12例测试者的ECAP阈值和行为阈值的关系 ,二者之间存在显著的相关性。结论 :ECAP的检出率高且波形稳定可靠 ,在临床人工耳蜗装置的调试中可作为对行为测试的补充 ;对于年幼儿童和首次开机的患者的调试尤其重要

Electrically evoked auditory nerve compound action potentials in Nucleus CI24M cochlear implant users

OBJECTIVE: To study the feasibility and clinical applicability of electrically evoked auditory nerve compound action potentials (ECAP) in young patients with Nucleus CI24M cochlear implants. METHOD: ECAPs have been recorded from 37 Nucleus CI24M cochlear implant users in response to monopolar electrical stimulation of the cochlea by using the neural response telemetry(NRT) software and the hardware. Behavioral thresholds and maximum comfortable levels were measured in 12 of those patients. RESULT: ECAPs could be recorded in 87.6% of all patients. Good relations were observed between ECAP threshold and behavioral threshold, but poor relations between ECAP threshold and the impedance of different electrodes. We also observed growth functions and threshold variations of ECAP across subjects for a given place as well as across electrodes within a subject. These findings might be that these particular physiological measures are related to the number of living neural fibers and the excitability of the auditory nerve to electrical stimulation. CONCLUSION: ECAPs were proved to be useful in adjusting the stimulation parameters of the cochlear implant speech processor in order to maximize an individual's performance with the device, especially in young children.