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低分子肝素治疗肾病综合征临床疗效观察
引用本文:袁圆,柴树人,王德光,陈薇. 低分子肝素治疗肾病综合征临床疗效观察[J]. 中国基层医药, 2002, 9(5): 391-392
作者姓名:袁圆  柴树人  王德光  陈薇
作者单位:230001,合肥,安徽省立医院肾内科
摘    要:
目的 观察低分子肝素(LMWH)对原发性肾病综合征的疗效和安全性。方法 30例原发性肾病综合征病人随机分为两组,对照组给予强的松。LMWH组在强的松治疗的基础上每日加用LMWH皮下注射。结果 LMWH组血纤维蛋白原(FIB),D-二聚体浓度明显下降,24h尿蛋白明显下降,血浆白蛋白明显上升。结论 LMWH可以明显改善原发性肾病综合征的高凝状态,延缓肾功能。

关 键 词:治疗 临床疗效 肾病综合征 低分子肝素 LMWH 安全性
修稿时间:2002-03-02

Effects of low molecular weight heparin on treatment of nephrotic syndrome
YUAN Yuan,CHAI Shuren,WANG Deguang,et al.. Effects of low molecular weight heparin on treatment of nephrotic syndrome[J]. Chinese Journal of Primary Medicine and Pharmacy, 2002, 9(5): 391-392
Authors:YUAN Yuan  CHAI Shuren  WANG Deguang  et al.
Affiliation:YUAN Yuan,CHAI Shuren,WANG Deguang,et al.Department of Nephrology,Anhui Provincal Hospital,Hefei,230001
Abstract:
Objective To investigate the effects and safety of low molecular weight heparin(LMWH) on treatment of primary nephrotic syndrome.Methods 30 cases of primary nephrotic syndrome were randomly divided into 2 groups,steroid was given in control group.LMWH was added in the treatment group with the dosage of per 24 hour.Results It was found that fibrinogen and the fibrinogen D dimer decreased obviously in concentration,and plasma urinary protein markedly increased in LMWH group.Conclusion LMWH can obviously improve the state of high agglutination of primary nephrotic syndrome and prevent the renal fuction from progressive damage.
Keywords:Nephrotic syndrome Low molecular weight heparin  
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