Rubidium-82 Positron Emission Tomography With Intravenous Ergonovine to Diagnose Vasospastic Angina |
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| Institution: | 1. Centre Hospitalier de l''Université de Montréal, Montréal, Québec, Canada;2. Montréal Heart Institute, Montréal, Québec, Canada;1. Department of Anesthesiology, The University of Texas at Houston, McGovern Medical School/Memorial Hermann Heart and Vascular Institute, Houston, Texas, USA;2. Department of Cardiology, The University of Texas at Houston, McGovern Medical School/Memorial Hermann Heart and Vascular Institute, Houston, Texas, USA;3. Department of Anesthesiology, Medical Faculty, RWTH Aachen University, Aachen, Germany;4. Department of Advanced Cardiopulmonary Therapies and Transplantation, The University of Texas at Houston, McGovern Medical School/Memorial Hermann Heart and Vascular Institute, Houston, Texas, USA;5. Department of Cardiac Surgery, The University of Texas Health Science Center at Houston, McGovern Medical School/Memorial Hermann Heart and Vascular Institute, Houston, Texas, USA;1. Division of Cardiac Surgery, Yale School of Medicine, New Haven, Connecticut, USA;2. Center for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Connecticut, USA;3. Joint Data Analytics Team, Yale New Haven Health System, New Haven, Connecticut, USA;4. Yale Aortic Institute, Yale School of Medicine, New Haven, Connecticut, USA;5. National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, Hebei, China;6. Yale Echocardiographic Core Laboratory, Yale-New Haven Health, New Haven, Connecticut, USA;1. Centre for Cardiovascular Innovation, Division of Cardiology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada;2. School of Nursing, University of British Columbia, Vancouver, British Columbia, Canada;3. Ethics Services, Providence Health Care, Vancouver, British Columbia, Canada;4. Assisted Dying Program, Vancouver Coastal Health, Vancouver, British Columbia, Canada;5. Division of Cardiology, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada;6. Montréal Heart Institute, Division of Cardiology, Department of Medicine, University of Montréal, Montréal, Québec, Canada |
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| Abstract: | The gold standard to diagnose vasospastic angina is intracoronary reactivity testing, which is performed selectively at dedicated centres. Noninvasive imaging with single-photon emission computerized tomography (SPECT) or echocardiography does not enable accurate localization of spasm or quantification of change in myocardial perfusion in response to an abnormal vasoreactivity. Rubidium-82 positron emission tomography myocardial perfusion imaging (82Rb PET-MPI) with intravenous ergonovine was used to diagnose refractory vasospastic angina in a patient with a complex ischemic syndrome, recent coronary stenting, and persistent atypical angina despite maximal tolerable doses of guideline-directed medical therapy. |
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