小儿肺炎支原体感染并发消化系统损害的临床特征及相关危险因素分析

目的观察分析小儿肺炎支原体感染合并消化系统损害的临床特征及相关危险因素。方法选取2014年1月至2016年12月在本院接受治疗的小儿肺炎支原体感染并发消化系统损害患儿58例作为本次研究的观察组,另选取同一时间段内在本院接受治疗的小儿肺炎支原体感染未并发消化系统损害患儿58例作为本次研究的对照组。观察分析患儿的临床特征,并通过单因素和多因素分析小儿肺炎支原体感染并发消化系统损害的相关危险因素。结果小儿肺炎支原体感染合并消化系统损害患儿的临床特征表现为恶心呕吐、腹泻、腹痛、急性肝炎、急性胰腺炎、急性胆囊炎及肝脾肿大等,其中恶心呕吐最为常见,占31.03%,而肝脾肿大较少见,占3.45%;两组患儿的年龄、病程等一般资料比较无显著差异(P>0.05),观察组患儿的发热时间及抗生素应用起始时间与对照组比较均有显著差异(P<0.05);经单因素分析显示,观察组患儿存在发热、发热时间>7d及抗生素的应用起始时间>病程的第5d与对照组比较均有显著差异(P<0.05);小儿肺炎支原体感染并发消化系统损害与发热、发热时间>7d、抗生素应用起始时间>病程第5d呈正相关(P<0.05)。结论小儿肺炎支原体感染并发消化系统损害以恶心呕吐为主要临床特征,因易与小儿支原体肺炎症状混淆,应加强消化系统监测,及时检查。经多因素Logistic回归性分析,发热、发热时间超过7d及抗生素的应用起始时间>病程的第5d是小儿肺炎支原体感染并发消化系统损害的独立险因素。

Clinical characteristics and related risk factors of Mycoplasma pneumoniae infection complicated with digestive system damage in children

Objective To observe and analyze the clinical characteristics and related risk factors of Mycoplasma pneumoniae infection complicated with digestive system damage in children.Methods 58 cases of children with Mycoplasma pneumoniae infection complicated by digestive system damage were enrolled in our hospital from January 2014 to December 2016.The observation group of this study was selected.Children who were treated in our hospital at the same time period were selected Mycoplasma pneumoniae infection was not complicated by digestive system damage in children with 58 cases as the study of the control group.To observe the clinical characteristics of children,and through single factor and multi-factor analysis of children with Mycoplasma pneumoniae infection complicated by digestive system damage related risk factors.Results The clinical characteristics of children with mycoplasma pneumonia complicated with digestive system were manifested as nausea and vomiting,diarrhea,abdominal pain,acute hepatitis,acute pancreatitis,acute cholecystitis and hepatosplenomegaly.Among them,nausea and vomiting were the most common,accounting for 31.03%(P>0.05).The duration of fever and the time of antibiotic application in the observation group were significantly higher than those in the control group(P<0.05),and the difference was significant(P>0.05)(P<0.05).There was significant difference between the two groups(P<0.05).There was significant difference between the two groups(P<0.05).There was significant difference between the observation group and the control group on the 5th day of the onset of fever,fever time>7 days and antibiotic application initiation time(P<0.05).There was a positive correlation between Mycoplasma pneumoniae infection complicated by digestive system and fever,fever time>7 days,antibiotic application initiation time>5 days.Conclusion Mycoplasma pneumoniae infection complicated by digestive system damage in patients with nausea and vomiting as the main clinical features,due to easy to confuse children with mycoplasma pneumonia symptoms,should strengthen the digestive system monitoring,timely examination.Multivariate logistic regression analysis,fever,fever time more than 7d and antibiotic application of the starting time>the fifth day of the course of childhood Mycoplasma pneumoniae infection complicated by digestive system damage independent risk factors.