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Basic Mechanisms of Pain in Osteoarthritis: Experimental Observations and New Perspectives
Institution:1. Department of Internal Medicine, Division of Rheumatology, Rush University Medical Center, Room 714, 1735 W Harrison Street, Chicago, IL 60612, USA;2. Department of Pharmacology, Northwestern University, Searle Building Room 8-510, 320 E Superior Street, Chicago, IL 60611, USA;1. Rheumatology Department, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Freeman Road, High Heaton, Newcastle upon Tyne NE7 7DN, UK;2. Spondylitis Program, Toronto Western Hospital, University Health Network, 399 Bathurst Street, Toronto, Ontario M5T 2S8, Canada;3. Schroeder Arthritis Institute, University Health Network;4. Department of Medicine, University of Toronto, Toronto, Ontario, Canada;5. Department of Immunology, University of Toronto, Toronto, Ontario, Canada;1. Division of Rheumatology, UMass Medical School, 119 Belmont Street, Worcester, MA 01605, USA;2. Department of Psychiatry, UCLA, 760 Westwood Plaza, C9-402, Los Angeles, CA 90095, USA;1. Department of Medicine, The George Washington University Medical Center, Arthritis and Rheumatism Associates, 2021 K Street, Northwest Suite 300, Washington, DC 20006, USA;2. Rheumatology Department, HFR Fribourg-hôpital Cantonal, Fribourg 1708, Switzerland;1. Division of Rheumatology, Department of Internal Medicine, University of California Irvine, Irvine, CA, USA;2. Northwestern University, Chicago, IL, USA;1. Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI, USA;2. The University of Michigan, 24 Frank Lloyd Wright Drive Lobby M, Ann Arbor, MI 48106, USA
Abstract:
Keywords:Osteoarthritis  Pain  Sensitization  DRG neurons  NGF  Innate immunity
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