动态血糖监测系统和扫描式血糖监测系统判断2型糖尿病患者黎明现象的一致性研究

目的:探讨基于动态血糖监测系统（CGMS）评价扫描式血糖监测系统判断2型糖尿病（T2DM）患者黎明现象的有效性。方法:采用便利抽样法,选取2019年6月—2020年6月于新乡市中心医院内分泌科住院的45例T2DM患者为研究对象。患者入院后先佩戴扫描式动态血糖监测系统,48 h后再佩戴CGMS行连续血糖监测,再过72 h...

Consistency of continuous glucose monitoring system and scanning blood glucose monitoring system in predicting dawn phenomenon in patients with type 2 diabetes mellitus

Objective To investigate the effectiveness of scanning glucose monitoring system in dawn phenomenon of patients with type 2 diabetes mellitus(T2DM)based on continuous glucose monitoring system(CGMS).Methods A total of 45 patients with T2DM hospitalized in the Endocrine Department of Xinxiang Central Hospital from June 2019 to June 2020 were selected as the research subjects by convenience sampling method.All selected patients were asked to wear the scanning glucose monitoring system after admission,and then the CGMS for continuous glucose monitoring after 48 hours.The scanning glucose monitoring system and the CGMS were taken off at the same time after 72 hours.The blood glucose analysis report of the same period was checked to determine whether the dawn phenomenon occurred.The consistency to determine dawn phenomenon was analyzed between CGMS and scanning blood glucose monitoring hy Kappa test.According to the CGMS judgment results,the receiver operating characteristic curve(ROC)of the scanning blood glucose monitoring system was drawn to evaluate the optimal tangent value of the night blood glucose for predicting dawn phenomenon and the next day fasting blood glucose for evaluating dawn phenomenon.Results Among the 45 study subjects,there was no statistical difference in determining the incidence of dawn phenomena between CGMS and scanning glucose monitoring system[55.56%(25/45)vs.46.67%(21/45),x²=0.711,P>0.05].Consistency analysis shower that Kappa value was 0.895,and the consistency of CGMS and scanning glucose monitoring system in judging dawn phenomenon was good(Kappa=0.895,95%C I 1.130-4.883,P<0.01).The optimal tangent value of night blood glucose for predicting dawn phenomenon was 8.31 mmol/L,and the optimal tangent value of the next day fasting blood glucose for evaluating dawn phenomenon was 7.25 mmol/L.The value of the area under the ROC curve were 0.729 and 0.803 respectively.Conclusions Scanning blood glucose monitoring can accurately judge the dawn phenomenon.When the night blood glucose value is 8.31 mmol/L,it indicates that the dawn phenomenon may occur.When the next day s fasting blood glucose value is 7.25 mmol/L,it indicates that the dawn phenomenon may already occur.