| 辛兰芷喷雾剂质量标准研究 |
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| 引用本文： | 赵良义,谢晓燕,邵艳新,李冬梅,鹿颐,温俊霞.辛兰芷喷雾剂质量标准研究[J].中国药房,2007,18(18):1391-1393. |
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| 作者姓名： | 赵良义 谢晓燕 邵艳新 李冬梅 鹿颐 温俊霞 |
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| 作者单位： | 1. 河北省胸科医院药剂科,石家庄市,050041
2. 河北省药品检验所,石家庄市,050011 |
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| 基金项目： | 河北省中医药管理局资助项目 |
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| 摘 要： | 目的:建立辛兰芷喷雾剂的质量标准。方法:采用TLC法对方中辛夷、板蓝根、白芷进行定性分析;用HPLC法对连翘苷进行含量测定。结果:TLC法可准确地对辛夷、板蓝根、白芷进行定性鉴别;连翘苷进样量在0.2~10.0μg范围内与峰面积积分值呈良好线性关系(r=0.9997);平均回收率为99.71%,RSD=1.85%(n=6)。结论:本方法简便、快速、重现性好,所建标准可用于本制剂的质量控制。
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| 关 键 词： | 辛兰芷喷雾剂 质量标准 薄层色谱法 高效液相色谱法 |
| 文章编号： | 1001-0408（2007）18-1391-03 |
| 收稿时间： | 2006-11-03 |
| 修稿时间： | 2006-11-032007-01-04 |
Quality Standard for Xinlanzhi Spray |
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| ZHAO Liangyi,XIE Xiaoyan,SHAO Yanxin,LI Dongmei,LU Yi,WEN Junxia.Quality Standard for Xinlanzhi Spray[J].China Pharmacy,2007,18(18):1391-1393. |
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| Authors: | ZHAO Liangyi XIE Xiaoyan SHAO Yanxin LI Dongmei LU Yi WEN Junxia |
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| Institution: | 1.Dept. of Pharmacy, Hebei Provincial Chest Hospital, Shijiazhuang 050041, China;2.Hebei Institute For Drug Control,Shijiazhuang 050011,China |
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| Abstract: | OBJECTIVE: To establish quality standard for Xinlanzhi Spray. METHODS: The qualitative analysis for Flos Magnoliae, Radix Isatidis and Radix Angelicae Dahuricae was performed using TLC, and the content of Forsythin in the Xinlanzhi spray was determined by HPLC. RESULTS: Flos Magnoliae, Radix Isatidis and Radix Angelicae Dahuricae could be accurately identified by TLC. There was good linearity for Forsythin within the range of 0. 2～ 10. 0μ g( r=0. 999 7) , and its average recovery was 99. 71% with RSD at 1. 85% ( n=6) . CONCLUSION: The method is simple, rapid and reproducible, and it can be used for the quality control of Xinlanzhi spray. |
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| Keywords: | Xinlanzhi spray Quality standard TLC HPLC |
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