| 茶多酚对镉致大鼠精子损伤的保护作用 |
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| 引用本文： | 王文祥,张文昌,廖惠珍. 茶多酚对镉致大鼠精子损伤的保护作用[J]. 福建医科大学学报, 2011, 45(5): 319-322,326 |
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| 作者姓名： | 王文祥 张文昌 廖惠珍 |
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| 作者单位： | 1. 福建医科大学,公共卫生学院营养与保健医学系,福州,350004
2. 福建医科大学,公共卫生学院职业与环境卫生学系,福州,350004 |
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| 摘 要： | 目的 探讨镉对大鼠精子损伤及茶多酚(TP)的保护作用.方法 50只清洁级SD系成年雄性大鼠,随机分为阴性对照组、模型组和TP干预组(50,100,200 mg/kg).模型组和各干预组以CdCl2腹部皮下注射染毒5周,干预组分别给予50,100,200 mg/kg TP灌胃.干预结束后取大鼠血、睾丸、附睾等组织进行相关...
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| 关 键 词： | 镉 茶 酚类 精子 DNA损伤 大鼠,Sprague-Dawley |
Protective Effect of Tea Polyphenols on Cadmium-induced Sperm Toxicity in Rats |
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| WANG Wenxiang,ZHANG Wenchang,LIAO Huizhen. Protective Effect of Tea Polyphenols on Cadmium-induced Sperm Toxicity in Rats[J]. Journal of Fujian Medical University, 2011, 45(5): 319-322,326 |
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| Authors: | WANG Wenxiang ZHANG Wenchang LIAO Huizhen |
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| Affiliation: | WANG Wenxiang1,ZHANG Wenchang2,LIAO Huizhen1 Fujian Medical University,School of Public Health,Fuzhou 350004,China 1.Department of Nutrition and Health Care,2.Department of Occupational and Environmental Health |
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| Abstract: | Objective To study the protective effects of tea polyphenols(TP) on cadmium-induced sperm toxicity in rats.Methods Fifty male adult Sprague-Dawley rats were randomly divided into 5 groups.Rats of model group and three TP groups were injected with cadmium at a dosage of 0.4 mg/kg.Animals of TP groups were simultaneously given TP at a dosage of 50,100 and 200 mg/kg respectively,once a day.After five weeks,samples of blood,testis and epididymis from all animals were collected for further analysis.Results(1) Co... |
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| Keywords: | cadmium tea phenols spermatozoa DNA damage rats Sprague-Dawley |
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