CT三维成像指导动脉导管未闭介入封堵术临床价值

目的 评价256层螺旋CT三维成像在动脉导管未闭(PDA)介入封堵术中的临床应用价值.方法 40例经超声诊断PDA患儿,随机分为术中造影组(A组)和CT导引组(B组),每组20例.A组根据术中造影显示作PDA封堵,B组根据CT检查结果指导PDA封堵.术中心脏超声监测,评价疗效.结果 B组PDA三维成像形态与A组术中造影PDA形态高度一致,PDA最窄内径分别为(3.88±1.59)mm和(3.63±1.41)mm,长度分别为(6.10±1.06)mm和(6.82±0.74)mm,组间差异均无统计学意义(P＞0.05);手术时间分别为(17.33±5.81)min和(34.30±9.11)min,术中接受X线辐射剂量分别为(33.93±11.00)mGy和(66.40±9.77)mGy,组间差异均有显著统计学意义(P＜0.001).但B组术前CT检查所接受辐射剂量为(119.79±29.45)mGy,累加术中剂量后总剂量较A组显著增高.结论 256层螺旋CT增强扫描及三维成像可替代术中造影,准确获取PDA患儿解剖影像资料,指导介入封堵手术,同时有效减少穿刺动脉损伤,缩短手术时间.但辐射剂量是需要考虑的因素.

Clinical value of CT 3D-imaging in guiding interventional occlusion therapy for PDA

Objective To discuss the clinical application value of 256-slice helical CT 3D-imaging in guiding interventional occlusion therapy for patent ductus arteriosus (PDA).Methods A total of 40 patients with sonography-proved PDA were randomly divided into group A (angiography group) and group B (CT-guided group) with 20 patients in each group.For the patients of group A,occlusion of PDA was performed based on the intraoperative angiography findings;and for the patients of group B,occlusion of PDA was carried out according to CT examination results.Intraoperative cardiac ultrasound monitoring was adopted and the curative effect was evaluated.Results The morphology of PDA demonstrated on CT 3Dimaging in group B was highly consistent with the configuration of PDA displayed on intraoperative angiography in group A.The most narrow diameters of PDA in group B and group A were (3.88±1.59) mm and (3.63±1.41) mm respectively,and the lengths of PDA in group B and group A were (6.1±1.06) mm and (6.82±0.74) mm respectively;the differences between the two groups were not statistically significant (P＞0.05).The time spent for surgery in group B and group A was (34.3±9.11) min and (17.33±5.81) min respectively,and the intraoperative X-ray radiation doses in group B and group A were (33.93±11.0) mGy and (66.48±9.77) mGy respectively;the differences between the two groups were statistically significant (P＜0.001).In group B,the preoperative X-ray radiation dose from CT examination was (119.79±29.45) mGy,when it was added to the intraoperative X-ray radiation dose the total cumulative radiation dose of group B was strikingly higher than that of group A.Conclusion Contrast-enhanced 256-slice helical CT scan and 3D-imaging technique can replace intraoperative angiography to get accurate anatomical imaging information of PDA,which are very helpful for the performance of interventional occlusion of PDA,meanwhile,it can effectively reduce the damage to the punctured artery and shorten the operation time.However,the radiation dose is a factor that should be taken into consideration.(J Intervent Radiol,2017,26:206-209)