射频消融与无水乙醇注射治疗原发性小肝癌的临床疗效分析

目的探讨射频消融与无水乙醇注射治疗原发性小肝癌患者的临床疗效。方法对98例原发性小肝癌患者（SHCC）进行射频消融（RFA）及经皮瘤体内无水乙醇注射治疗（PEIT）。98例病人随机分为RFA组49例共60个病灶,PEIT组（对照组）49例共76个病灶。比较患者RFA及PElT治疗后的近期疗效（肿瘤消融率）,第1、2年生存率和术后并发症。结果两组患者术后均无严重并发症;肿瘤消融率RFA组为93.8%;PEIT为组77.5%;RFA组肿瘤消融率高于PEIT组（P〈0.05）。RFA组术后1、2年生存率分别为95.9%9、1.8%;PEIT组病术后1、2年生存率分别为85.7%7、7.5%;RFA组1,2年生存率高于PRIT组（P〈0.05）。结论对于SHCC的治疗,RFA临床疗效优于PEIT;但位于肝脏表面、靠近第一,二,三肝门的SHCC,以PEIT较为安全。

Clinical effect of radiofrequency ablation therapy and percutaneous ethanol injection therapy on small hepatocellular carcinoma

Objective To study clinical effect radiofrequency ablation(RFA) and percutaneous ethanol injection therapy(PEIT) on small hepatocellular carcinoma(SHCC).Methods 98 patients of primary small hepatocellular carcinoma(SHCC) were treated with radiofrequency ablation(RFA) or percutaneous intratumoral ethanol injection therapy(PEIT).The tumor ablation rate,survival rate,postoperative complications between RFA and PEIT in the first two years were observed.Results There were no serious complications in the two grou...