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综合祛痰治疗在慢性阻塞性肺疾病稳定期患者家庭护理中的重要作用
引用本文:兰娜. 综合祛痰治疗在慢性阻塞性肺疾病稳定期患者家庭护理中的重要作用[J]. 中国医药科学, 2012, 0(16): 21-23,34
作者姓名:兰娜
作者单位:青海省中医院急诊科
摘    要:
目的探索综合祛痰治疗在COPD稳定期患者家庭护理中的疗效。方法 120例于笔者所在医院治疗的COPD患者,出院后被分为对照组及观察组,对照组给予沐舒坦片及复方鲜竹沥祛痰治疗,观察组给予盐酸氨溴索注射液超声雾化吸入加复方鲜竹沥祛痰治疗,两组1年后进行评估。结果两组患者均于参与研究1年后进行评估,症状评估对照组mMRC分级0~1患者34例(57.0%),观察组47例(78.3%),观察组显著高于对照组,差异有统计学意义(P=0.01);肺功能评估GOLD1~2对照组39例(65.0%),观察组46例(77.7%),两组差异无统计学意义(P=0.16);每年急性加重次数评估≤1次对照组15例(25.0%),观察组28例(46.7%),观察组高于对照组,差异有统计学意义(P=0.01);合并症评估,两组家庭治疗1年内均无死亡患者,观察组在代谢综合症、焦虑和抑郁发生率明显低于对照组,差异有统计学意义(P=0.02,P=0.03);综合评估,对照组A组11例(18.3%),观察组21例(35.0%),对照组显著低于观察组,差异有统计学意义(P=0.04)。对照组D组25例(46.7%),观察组11例(18.3%),对照组显著高于观察组,差异有统计学意义(P=0.01)。结论采用盐酸氨溴索超声雾化吸入联合口服复方鲜竹沥化痰治疗在COPD稳定期康复治疗中疗效显著,值得临床推广使用。

关 键 词:慢性阻塞性肺疾病  超声雾化吸入  稳定期

Integrated expectorant treatment of home care in COPD patients with stable stage
LAN Na. Integrated expectorant treatment of home care in COPD patients with stable stage[J]. China Medicine and Pharmacy, 2012, 0(16): 21-23,34
Authors:LAN Na
Affiliation:LAN Na Department of Emergency,Traditional Chinese Medical Hospital of Qinghai Province,Xining 810000,China
Abstract:
Objective To explore the effect of integrated expectorant treatment in home cares in COPD patients with stable stage.Methods 120 COPD patients in our hospital were divided into the observation group and control group,the control group were given the mucosolvan sheets and the compound Xianzhuli expectorant treatment while the observation group was treated with ultrasonic atomizing inhalation of ambroxol hydrochloride injection plus the compound Xianzhuli expectorant treatment.Two groups were assessed after one year.Results 34 patients(57.0%) were mMRC class 0 to 1 in the control group with 47 cases(78.3%) in the observation group.The difference was statistically significant(P=0.01).There were 39 cases(65.0%) whose lung function between GOLD 1 to 2 in the control group and 46 cases(77.7%)in the observation group.No significant difference was found(P=0.16).Each year with acute exacerbation which was lower than 1 in the control group was 15 cases(25.0%) and in the observation group was 28 cases(46.7%),the two groups were significantly different(P=0.01).There was no death within one year in the both groups.The incidence of metabolic syndrome,anxiety and depression of the control group was significantly lower(P=0.02,P=0.03).Conclusion Ambroxol hydrochloride ultrasonic atomizing inhalation of combined oral the compound Xianzhuli phlegm treatment has an evident effect in the rehabilitation treatment of COPD stable stage and worthy of using in the clinical.
Keywords:COPD  Ultrasonic atomizing inhalation  Stable stage
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