| 吡柔比星膀胱内灌注在膀胱移行细胞癌术后治疗中的效果观察 |
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| 引用本文： | 张俭. 吡柔比星膀胱内灌注在膀胱移行细胞癌术后治疗中的效果观察[J]. 现代预防医学, 2011, 38(7): 1349-1350,1353 |
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| 作者姓名： | 张俭 |
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| 作者单位： | 河北邢台市人民医院泌尿外科,邢台,054000 |
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| 摘 要： | [目的]探讨吡柔比星膀胱内灌注在膀胱移行细胞癌术后治疗中的效果。[方法]选取2007年1月~2009年1月于某院进行手术治疗的72例膀胱移行细胞癌患者为研究对象,将其分为对照组(丝裂霉素组)36例和观察组(吡柔比星组)36例,分别采用丝裂霉素和吡柔比星进行膀胱内灌注治疗,后将两组患者复发率、平均复发时间、不良反应及灌注前后血清ICAM-1、VCAM-1、VEGF及HA水平进行检测及比较。[结果]观察组的复发率低于对照组,平均复发时间长于对照组,不良反应发生率低于对照组,而治疗后血清ICAM-1、VCAM-1、VEGF及HA水平均低于对照组,经比较,P均﹤0.05,差异均有统计学意义。[结论]吡柔比星膀胱内灌注在膀胱移行细胞癌术后治疗中的效果明显,值得临床推广应用。
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| 关 键 词： | 吡柔比星 丝裂霉素 膀胱内灌注 膀胱移行细胞癌 术后治疗 效果 |
OBSERVATION OF THE EFFECTS OF PIRARUBICIN THROUGH INTRAVESICAL PERFUSION AFTER THE SURGERY OF TRANSITIONAL CELL CARCINOMA OF BLADDER |
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| ZHANG Jian. OBSERVATION OF THE EFFECTS OF PIRARUBICIN THROUGH INTRAVESICAL PERFUSION AFTER THE SURGERY OF TRANSITIONAL CELL CARCINOMA OF BLADDER[J]. Modern Preventive Medicine, 2011, 38(7): 1349-1350,1353 |
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| Authors: | ZHANG Jian |
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| Affiliation: | ZHANG Jian.(Department of Urology,the People's Hospital of Xingtai City,Xingtai 054000,China) |
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| Abstract: | [Objective]To study the effects of pirarubicin through intravesical perfusion after the surgery of transitional cell carcinoma of bladder.[Methods]72 transitional cell carcinoma of bladder patients with surgery in our hospital from January 2007 to January 2009 were selected as research subjects,and all the patients were divided into control group(Mitomycin group)and observation group(pirarubicin group),36 cases in each group.Then the recurrence rate,average recurrence time,adverse reactions and serum ICAM-1... |
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| Keywords: | Pirarubicin Mitomycin Intravesical Transitional cell carcinoma of bladder Treatment Effects |
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