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氟伐他汀联合缬沙坦对慢性心力衰竭患者血清BNP水平和心功能的影响
引用本文:刘聪. 氟伐他汀联合缬沙坦对慢性心力衰竭患者血清BNP水平和心功能的影响[J]. 现代预防医学, 2011, 38(7): 1381-1382,1385
作者姓名:刘聪
作者单位:海南省琼海市人民医院心内科,琼海,571400
摘    要:
[目的]观察氟伐他汀联合缬沙坦对慢性充血性心力衰竭患者血清BNP水平和心功能的影响。[方法]100例慢性充血性心力衰竭患者随机分为治疗组和对照组。对照组给予缬沙坦及常规治疗,治疗组在此基础上加用氟伐他汀,疗程均为1年。比较两组治疗前后血清BNP水平的变化和心功能疗效及心脏彩超指标。[结果]治疗组1年后血清BNP水平较对照组显著下降(P﹤0.05);心功能改善总有效率显著优于对照组(P﹤0.05);左心室射血分数(LVEF)、左室舒张末内径(LVEDd)均较对照组有明显改善(P﹤0.05)。[结论]氟伐他汀联合缬沙坦治疗慢性充血性心力衰竭能显著降低患者血清BNP水平,明显改善心功能,疗效优于单加缬沙坦。

关 键 词:氟伐他汀  缬沙坦  脑钠肽  心力衰竭

AFFECTION OF COMBINED TREATMENT WITH FLUVASTATIN AND VALSARTAN ON BNP LEVEL AND HEART FUNCTION OF CHRONIC CONGESTIVE HEART FAILURE PATIENTS
LIU Cong. AFFECTION OF COMBINED TREATMENT WITH FLUVASTATIN AND VALSARTAN ON BNP LEVEL AND HEART FUNCTION OF CHRONIC CONGESTIVE HEART FAILURE PATIENTS[J]. Modern Preventive Medicine, 2011, 38(7): 1381-1382,1385
Authors:LIU Cong
Affiliation:LIU Cong.(Qionghai City People's Hospital in Hainan,Qionghai 571400,China)
Abstract:
[Objective]To observe the affection of combined treatment with fluvastatin and valsartan on heart function(HF)and BNP level of chronic congestive heart failure(CCHF)patients.[Methods]100 cases were divided into therapy group and control group.The control group was treated with valsartan and therapy group was treated with fluvastatin based on control group for 1 year as a course.BNP level,HF and echocardiography indictors were detected.[Results]HF,LVEF and LVEDd in therapy group were improved than those in c...
Keywords:Fluvastatin  Valsartan  BNP  Heartfailure  
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