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| 腹腔热化疗对胃肠道恶性肿瘤患者T淋巴细胞亚群及SIL—2R水平的影响 | |
| 引用本文： | 冉江华,张家骅,郭群,王曦. 腹腔热化疗对胃肠道恶性肿瘤患者T淋巴细胞亚群及SIL—2R水平的影响[J]. 临床肿瘤学杂志, 1999, 4(3): 27-28 |
| 作者姓名： | 冉江华 张家骅 郭群 王曦 |
| 作者单位： | 昆明医学院第二附属医院普外科 |
| 摘 要： | 目的:评估腹腔灌注热化疗(IPHC)对胃肠道恶性肿瘤患者免疫功能的影响.方法:对32例胃肠道恶性肿瘤患者术后腹腔灌注热化疗并测定外周血T淋巴细胞亚群(T-LS)和血清白细胞介素Ⅱ受体(SIL-2R)水平,与20例健康对照组进行比较.结果:行IPHC前,CD_3~ 、CD_4~ 、CD_8~ 、CD_4~ /CD_8~ 较对照组降低,SIL-2R升高,行IPHC后CD_3~ 、CD_4~ 、CD_8~ 、CD_4~ /CD_8~ 明显下降(P<0.01),SIL-2R降低(P<0.01).结论:腹腔灌注热化疗能明显提高患者免疫功能. |
| 关 键 词： | 腹腔热化疗 胃肠道恶性肿瘤 T-LS SIL-2R |
Effect of intraperitoneai hyperthermo chemotherapy on T-LS and SIL-2R level in the patients with gastrointestinal malignant tumor. |
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| Ran Jianghua,Zhang Jiahua,Guo Qung,et al.. Effect of intraperitoneai hyperthermo chemotherapy on T-LS and SIL-2R level in the patients with gastrointestinal malignant tumor.[J]. Chinese Clinical Oncology, 1999, 4(3): 27-28 | |
| Authors: | Ran Jianghua Zhang Jiahua Guo Qung et al. |
| Affiliation: | Ran Jianghua,Zhang Jiahua,Guo Qung,et al. Department of General Surgery,the Second Affiliated Hospital of Kunming Medical College,Kunming 650101 |
| Abstract: | Objective:To evaluate the effect of Intraperitoneal hyperthermo chmotherapy (IPHC) on immunologic function of patients with gastrointestinal malignant tumor (GMT) Methods: We determined the serum T - lymphocyte subsets (IL - S) and In-torleakin - 2 Resepter (SIL - 2R) of 32 patients with GMT after IPHC, and compaired the two Index with 20 healthy control group. Results: Before IPHC the serum CD3 , CD4 , CD8 , CD4 /CD8 are Higner and SIL - 2R are lower than control group, after IPHC, CD3 ,CD4 ,CD8 and CD4 /CD8 increased obviously (P<0.01) and the SIL - 2R decreased signifcantly. (P< 0.01) Conclusions: The IPHC can improve the patient's immunologic function. |
| Keywords: | Intraperitoneal hypertherimo chmotherapy Gastrointestinal malignant tumor T- LS SIL- 2R |
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