Calcium oxalate crystal deposition in a patient with Aspergilloma due to Aspergillus niger |
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| Authors: | Miku Oda Takeshi Saraya Megumi Wakayama Kazutoshi Shibuya Yukari Ogawa Toshiya Inui Emi Yokoyama Manami Inoue Hiroaki Shimoyamada Masachika Fujiwara Tomohiro Ota Hajime Takizawa Hajime Goto |
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| Affiliation: | 1.Department of Respiratory Medicine, Kyorin University School of Medicine, Tokyo, Japan;;2.Department of Surgical Pathology, Toho University School of Medicine, Tokyo, Japan;;3.Department of Respiratory Medicine, Shiseikai Daini Hospital, Tokyo, Japan;;4.Department of Pathology, Kyorin University School of Medicine, Tokyo, Japan |
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| Abstract: | ![]()
Discrimination between aspergilloma and chronic necrotizing pulmonary aspergillosis (CNPA) based on radiological findings can difficult. We describe a patient with aspergilloma and organizing pneumonia that was possibly caused by Aspergillus niger infection and radiologically mimicked CNPA. A postmortem histological analysis showed diffuse alveolar damage that had originated in peri-cavitary lung parenchyma. Calcium oxalate or Aspergillus niger was located inside, but not outside the cavity in the right upper lobe. Calcium oxalate or other unknown hyphal bioactive components might provoke severe lung inflammation not only adjacent to the cavity, but also on the contralateral side.KEY WORDS : Calcium oxalate crystal deposition, aspergilloma, black deposits, Aspergillus niger |
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