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Cryptococcal meningitis in a patient treated with infliximab |
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| Authors: | Muñoz Patricia Giannella Maddalena Valerio Maricela Soria Teresa Díaz Fernando Longo Javier Lopez Bouza Emilio |
| Affiliation: | 1. Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario “Gregorio Marañón”, University of Madrid, 28007 Madrid, Spain;2. Department of Clinical Medicine, Policlinico Umberto I, University “La Sapienza,” Rome, Italy;3. Department of Neurology, Hospital General Universitario “Gregorio Marañón”, University of Madrid, 28007 Madrid, Spain;4. Department of Rheumatology, Hospital General Universitario “Gregorio Marañón”, University of Madrid, 28007 Madrid, Spain |
| Abstract: | Infliximab, a tumor necrosis factor-alpha inhibitor, is increasingly used for the therapy of different inflammatory conditions. We report the first case of cryptococcal meningitis in a patient treated with infliximab and other immunosuppressive agents, and review a further 5 reported cryptococcal infections. All of them involved fungal pneumonia. Outcome was favorable in all cases. |
| Keywords: | Infliximab Cryptococcus neoformans Rheumatoid arthritis Immunosuppressed host Meningitis Pneumonia |
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