颌骨恶性成釉细胞瘤10例报道

目的：探讨恶性成釉细胞瘤的临床表现、X线特征及治疗方法。方法：复习上海第二医科大学附属第九人民医院口腔颌面外科1991～2003年以来收治的10例恶性成釉细胞瘤(均经病理证实)患者,随访1～8a,对临床表现、诊断、治疗效果等进行回顾性分析。结果：10例患者中,男性5例,女性5例;年龄最大60岁,最小22岁;上颌骨4例,下颌骨6例。除2例自动放弃手术治疗外,其余均行颌骨部分切除,改良根治性或肩胛舌骨上颈淋巴清扫术,同期皮瓣修复,创口愈合良好。获得随访者,外观及功能恢复满意,无复发。结论：恶性成釉细胞瘤是一种低度恶性肿瘤,手术是其唯一根治方法。

Malignant ameloblastoma of the jaw:An analysis of 10 consecutive cases

PURPOSE: To investigate the clinical and radiographic manifestations of malignant ameloblastoma of the jaw and methods for treatment. METHODS: 10 consecutive cases of malignant ameloblastoma were treated in the Department of Oral and Maxillofacial Surgery, Ninth People's Hospital,Shanghai Second Medical University between 1991 and 2003. All the cases were proved to be malignant ameloblastoma by surgical pathology and followed up for 1 to 8 years. This paper reviewed the clinical manifestation, diagnosis and treatment of these 10 cases. RESULTS: Among the 10 cases of malignant ameloblastoma ,5 were female,5 were male ,aged from 22 to 60 years.4 cases were located in the maxilla, and 6 cases in the mandible.All the patients underwent partial mandibulectomy or maxillectomy combined with modified radical neck dissection or supraomohyoid dissection with flap repair at the same time.The follow up outcomes were satisfactory both in appearance and function without recurrence. CONCLUSION: Malignant ameloblastoma is a kind of low degree malignant tumors. Diagnosis is made by pathology. Operation is the only radical method of therapy.