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Design of a Potent CB1 Receptor Antagonist Series: Potential Scaffold for Peripherally-Targeted Agents
Authors:Robert L. Dow,Philip A. Carpino,Denise Gautreau,John R. Hadcock,Philip A. Iredale,Dawn Kelly-Sullivan,Jeffrey S. Lizano,Rebecca E. O’Connor,Steven R. Schneider,Dennis   O. Scott,Karen M. Ward
Affiliation:Pfizer Worldwide Research and Development, Eastern Point Road, Groton, Connecticut 06340, United States
Abstract:
Keywords:Obesity   cannabinoid receptor   antagonist   clearance   polar surface area   multidrug resistanceprotein 1   ligand efficiency   ligand-lipophilicityefficiency
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