Design of a Potent CB1 Receptor Antagonist
Series: Potential Scaffold for Peripherally-Targeted Agents |
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Authors: | Robert L. Dow,Philip A. Carpino,Denise Gautreau,John R. Hadcock,Philip A. Iredale,Dawn Kelly-Sullivan,Jeffrey S. Lizano,Rebecca E. O’Connor,Steven R. Schneider,Dennis
O. Scott,Karen M. Ward |
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Affiliation: | Pfizer Worldwide Research and Development, Eastern Point Road, Groton, Connecticut 06340, United States |
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Abstract: |
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Keywords: | Obesity cannabinoid receptor antagonist clearance polar surface area multidrug resistanceprotein 1 ligand efficiency ligand-lipophilicityefficiency |
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