Wart with Depigmented Halo and Generalized Vitiligo |
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Authors: | Takamichi Ito Yuichi Yoshida Koji Adachi Masutaka Furue Osamu Yamamoto |
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Institution: | *Division of Dermatology, Department of Medicine of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8503, Japan;†Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan |
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Abstract: | Depigmented haloes sometimes appear around melanocytic tumors or non-melanocytic
tumors, but coexistence of warts and depigmented haloes is extremely rare. We report
here an unusual case of warts accompanied by depigmented haloes and
subsequently-triggered generalized vitiligo. A 55-year-old Japanese man presented
with a 3-year history of brown nodules on the back, upper eyelid and dorsum of
the left hand. Depigmented haloes appeared around the noldules and then gradually spread
over a wide area, resulting in the development of generalized vitiligo. He had no history
of antecedent treatment for these lesions before consultation. Histopathologically,
the lesion showed papillomatosis and hyperkeratosis with lymphocytic exocytosis
into the epidermis, which compatible to warts. Based on these clinical and
histopathologic findings, a diagnosis of warts with depigmented halo and
subsequently-triggered generalized vitiligo was made. None of the warts had resolved
spontaneously after the appearance of haloes, and the depigmented haloes and generalized
vitiligo remain unchanged. |
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Keywords: | depigmented halo verruca vitiligo wart |
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