移动电话微波辐射对人皮肤角朊细胞损伤的研究

目的探讨移动电话微波辐射对体外培养人皮肤角朊细胞的影响.方法体外培养的人皮肤角朊细胞(HaCaT细胞)暴露于或假暴露于频率为1.8GHz、SAR为1W/Kg、2W/Kg、3W/kg的模拟移动电话微波辐射4小时后,检测乳酸脱氢酶(LDH)活力及细胞死亡率.结果在SAR 3W/kg组可引起细胞死亡率的增高,为13.4±0.1,与对照组12.0±0.1相比,有显著性差异(P＜0.05);在SAR 2W/Kg和SAR 3W/kg组,培养液中LDH活力值(U/L)增高,分别为1342.7±226.4和1414.1±134.7,与对照组LDH活力值1017.6±204.5U/L和985.9±274.9U/L相比,有显著性差异(P＜0.05).结论移动电话微波辐射对体外培养人皮肤角朊细胞有损伤作用.

The Effect of Mobile Phone Microwave Radiation on Cultured Keratinocytes

Objective To investigate the effect of mobile phone microwave radiation on cultured keratinocytes. Methods The keratinocytes were exposed or non-exposed to microwave radiation for 4 hours with frequency of 1 8GHz, the average specific absorption rate (SAR) at three levels of 1W/Kg, 2W/Kg and 3W/Kg, respectively.The lactate dehydrogenases (LDH) and cell death rate were detected. Results The level of LDH and cell death rate in the exposure groups with SAR of 3W/Kg were significantly higher than those in the control groups. The level of LDH was also found significantly increased in the exposure groups with SAR of 2W/Kg. However, no significant difference was found between the exposed group SAR of 1W/Kg and controls. Conclusions The microwave radiation of mobile phone can cause some damage on keratinocytes.