地佐辛应用于瑞芬太尼静脉麻醉后患者的痛觉过敏观察

目的探析地佐辛对瑞芬太尼静脉麻醉术后患者疼痛过敏的影响，评价其镇痛的安全性以及有效性。方法选择腹腔镜下手术患者60例为研究对象，回顾性分析其临床资料。结果观察组患者要求进行镇痛距手术结束时间明显比对照组长（P〈0．05）；观察组患者在T1、T2、T3时点Ramsay评分明显优于对照组（P〈0．05），T3时点观察组VAS评分明显优于对照组（P〈0．05）；苏醒和拔管的时间、呼吸抑制、恶习呕吐等差异不具有统计学意义（P〉0．05）。结论地佐辛能有效的得到控制或者改善疼痛过敏，有效地减轻患者术后的疼痛感，安全性高。

Application of dezocine for hyperalgesia in patients receiving intravenous anesthesia with remifentanil

Objective To investigate the effect of dezocine on hyperalgesia in patients receiving intravenous anesthesia with remifentanil, and to assess the safety and efficacy of dezocine. Methods Sixty patients who had undergone laparoscopic surgery were included in this study. The clinical data were retrospectively analyzed. Results The duration from the beginning of analgesis to the completion of surgery was markedly longer in the study group of patients than the control group （P〈0.05）. The study group was superior to the control group in Ramsay score at T1, T2, and T3 （P〈0.05）; VAS score was better in the study group than in the control group at T3 （P〈 0.05）. Time to awakening and tube drawing, respiratory depression, and nausea and vomiting did not differ significantly （P〉0.05）. Conclusions Dezocine can effectively control or improve hyperalgesia and relieve postoperative pain in patients, and it has higher safety.