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我院396例药物致皮肤不良反应报告分析
引用本文:林燕琼,林维嘉.我院396例药物致皮肤不良反应报告分析[J].中国药房,2010(38):3620-3621.
作者姓名:林燕琼  林维嘉
作者单位:厦门市第一医院,厦门市361003
摘    要:目的:了解引起皮肤不良反应的药品种类及其发生的相关因素。方法:对我院皮肤科2004~2008年收集到的396例药物致皮肤不良反应病例进行分类统计和分析。结果:396例皮肤不良反应病例涉及的药物共有149种,其中抗感染药居首位,有211例(占53.28%),其次为中药制剂,有49例(占12.37%);给药途径以静脉滴注为主,有213例(53.79%);一般不良反应345例,严重不良反应51例,其中新的不良反应17例。结论:临床应重视合理用药,预防和减少药物引起的皮肤不良反应。

关 键 词:皮肤不良反应  分析  合理用药

Analysis of 396 Cases of Cutaneous ADR Induced by Drugs
LIN Yan-qiong,LIN Wei-jia.Analysis of 396 Cases of Cutaneous ADR Induced by Drugs[J].China Pharmacy,2010(38):3620-3621.
Authors:LIN Yan-qiong  LIN Wei-jia
Institution:(Xiamen Municipal First Hospital,Xiamen 361003,China)
Abstract:OBJECTIVE:To investigate the type of drugs which cause cutaneous ADR and its relevant factors.METHODS:396 cases of cutaneous ADR induced by drugs,which collected from the department of dermatology in our hospital from 2004 to 2008,were classifited and analyzed statistically.RESULTS:396 ADR cases involved 149 kinds of drugs,among which 211 ADR cases were induced by antibiotics(53.28%)and 49 cases by TCM preparations(12.37%);213 cases were caused by intravenous injection(53.79%).There were 345 conventional ADR cases and 51 severe ADR cases,among which there were 17 new ADR cases.CONCLUSION:Great importance should be attached to rational use of drugs to prevent and reduce the occurrence of cutaneous ADR induced by drugs.
Keywords:Cutaneous ADR  Analysis  Rational use of drugs
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