甲磺酸瑞波西汀联合西沙必利治疗功能性消化不良的疗效观察

目的:观察甲磺酸瑞波西汀联合西沙必利治疗功能性消化不良的疗效。方法:146例功能性消化不良患者随机分成2组。治疗组76例,给予甲磺酸瑞波西汀胶囊联合西沙必利片治疗;对照组70例,给予西沙必利片治疗。疗程均为4周。结果:治疗组与对照组的总有效率分别为84.21%、61.43%,差异有统计学意义(P<0.05);治疗结束8周后随防,治疗组与对照组的复发率分别为12.50%、30.23%,差异有统计学意义(P<0.05)。结论:甲磺酸瑞波西汀联合西沙必利治疗功能性消化不良疗效好。

Efficacy Observation of Reboxetine Mesylate Combined with Cisapride in the Treatment of Functional Dyspepsia

OBJECTIVE：To evalvuate the clinical efficacy of reboxetine mesylate combined with cisapride in the treatment of functional dyspepsia（FD）.METHODS：146 patients with FD were randomly divided into 2 groups.Treatment group received Reboxetine mesylate capsules and Cisapride tablets for 4 weeks（n=76）.Control group received Cisapride tablets for 4 weeks（n=70）.RESULTS：The total effective rates were 84.21% for treatment group and 61.43% for control group,significant difference was found between 2 groups（P0.05）.Following up after 8 weeks of treatment,the relapse rates were 12.50% for treatment group and 30.23% for control group,significant difference was found between 2 groups（P0.05）.CONCLUSION：Reboxetine mesylate combined with cisapride has satisfactory efficacy in the treatment of functional dyspepsia.