松针提取物对小鼠肠系膜微循环障碍的影响

目的:研究松针提取物对小鼠肠系膜微循环障碍的影响。方法:采用小鼠肠系膜微循环实验,空肠袢滴加肾上腺素0.2mL(1∶10000),分别于滴加前及滴加2、5min时观察微血管管径大小、微血流速度、毛细血管网交点开放数的变化情况。结果:松针提取物能明显改善肾上腺素引起的微静脉、微动脉管径的收缩;提高血管内微血流的速度,但作用时间不长;同时还能改善毛细血管网交点开放数的减少。结论:松针提取物能改善肾上腺素引起的小鼠肠系膜微循环障碍,有一定的活血作用。

Effects of the Extracts of Pine Needles on Mesenteric Microcirculation of Mice

OBJECTIVE： To study the effect of the extracts of pine neddles on the mesenteric microcirculation of mice. METHODS： In mice mesenteric microcirculation study, 0.2 mL adrenaline hydrochloride was added into jejunum （1 ： 10 000）. The vessel diameter, blood blowing velocity, the junction mount of capillary network were observed and recorded at the time of before adding adrenaline hydrochloride and 2 minutes and 5 minutes after adding adrenaline hydrochloride. RESULTS： The extracts of pine needles could remarkably inhibit the venule contraction and arteriole contraction; it could improve the blood blowing velocity for a short period and increase the opening points of the junction of capillary network. CONCLUSION： The extracts of pine needles can improve on the mesenteric microcirculation and activate blood flow.