四川省凉山州布拖县HIV抗体阳性孕产妇母婴阻断措施实施情况分析

目的分析四川省凉山州布拖县预防艾滋病母婴传播措施的实施情况及母婴阻断效果。方法对2008年1月～2010年6月发现的177例HIV抗体阳性孕产妇的资料进行回归性分析,对其孕期服用抗病毒药物情况、妊娠结局、分娩方式、婴儿喂养方式、婴儿HIV感染情况等进行分析。结果 177例患者中,最终失访的有25例。剩余的152例中,终止妊娠的有5.9%(9/152),118例已分娩。还有25例处于妊娠期。分娩的产妇中有64.4%(76/118)服用过抗病毒药物,97.5%(115/118)为阴道分娩。已分娩的118例中,8例为死胎、死产,17例婴儿因各种原因死亡。存活的93例婴儿中,75.3%(70/93)服用了抗病毒药物,84.9%(79/93)采用人工喂养。8例婴儿在满18月龄时检测了HIV抗体,其中1例为阳性,其余为阴性。阻断率为87.5%(7/8)。结论布拖县对HIV阳性孕产妇所实施的综合干预措施对降低艾滋病母婴传播起到了良好作用,但仍需进一步加强。

Analysis of the effect of PMTCT intervention in Butuo County

OBJECTIVE To analyze the effect of prevention mother-to-child transmission(PMTCT)intervention among HIV positive pregnant and puerperant women in Butuo County of Sichuan Province.METHODS Clinical features of 177 HIV positive pregnant and puerperant women and the effect of PMTCT intervention as well as their infants from Jan 2008 to Jun 2010 were analyzed.RESULTS 64.4% pregnant women had taken anti-HIV drugs;75.3% infants had taken anti-HIV drugs;84.9% infants received artificial feeding;There were 8 infants had been tested HIV antibody at the end of the 18th month,only one showed be positive.CONCLUSION The intervention for PMTCT is effective and feasible,but still needs to be strengthened.