| 同时测定呋麻滴鼻液中两组分含量 |
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| 引用本文： | 薛光辉,刘伟,包丽丽,杨宏昕.同时测定呋麻滴鼻液中两组分含量[J].数理医药学杂志,2006,19(5):537-538. |
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| 作者姓名： | 薛光辉 刘伟 包丽丽 杨宏昕 |
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| 作者单位： | 内蒙古自治区医院药剂处,呼和浩特,010017 |
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| 摘 要： | 目的:建立同时测定呋麻滴鼻液中呋喃西林和盐酸麻黄碱的含量的方法。方法:采用紫外分光光度法,检测波长为375nm和257nm。结果:盐酸麻黄碱在0.1~0.5mg·mL-1范围内与吸收度值有良好的线性关系,由此可推出呋麻滴鼻液中盐酸麻黄碱的浓度C麻=1.1387(A257-0.819A375)-0.0001,平均回收率为100.23%,RSD为0.25%。结论:该法简便、灵敏、结果准确,可用于本制剂的含量测定和质量控制。
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| 关 键 词： | 紫外分光光度法 呋麻滴鼻液 含量测定 |
| 文章编号： | 1004-4337（2006）05-0537-02 |
| 收稿时间： | 2005-11-10 |
| 修稿时间： | 2005年11月10 |
Method for Simultaneous Determination of Nitrofural and Ephedrine Hydrochloride in Nose Drops |
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| Xue Guanghui,et alJZ.Method for Simultaneous Determination of Nitrofural and Ephedrine Hydrochloride in Nose Drops[J].Journal of Mathematical Medicine,2006,19(5):537-538. |
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| Authors: | Xue Guanghui [JZ] |
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| Abstract: | Objective: To establish a method for simultaneous determination of nitrofural and ephedrine hydrochloride in nose drops. Methods: Ultravoilet spectrophotometry detection wavelength was 375nm and 257nm. Results: The calibration curves was linear in the range of 0.1~0.5 mg·mL~ -1 for ephedrine hydrochloride,The average recovery was 100.23%(RSD=0.25%). Conclusion:The method is simple and accurate,the quality of the nose drops can be controlled using the method. |
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| Keywords: | ultravoilet spectrophotometry nitrofural and ephedrine nose drops content determination |
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