孕酮监测在异位妊娠早期诊断中的价值

目的探讨孕酮及血清人绒毛膜促性腺激素（β-HCG）检测在异位妊娠早期诊断中的价值。方法分别检测42例异位妊娠患者和同期40例早期正常宫内妊娠妇女的孕酮和血清β-HCG的浓度值。结果异位妊娠组孕酮和血清β-HCG值明显低于正常宫内妊娠组,差异有统计学意义（P〈0.01）。若以孕酮〈15ng/mL作为诊断异位妊娠的临界点,其敏感度为90.48%,特异度为92.50%,阳性预测值为92.68%,诊断符合率91.46%。结论孕酮与血清β-HCG监测可提高异位妊娠早期诊断的敏感性和特异性。

Value of progesterone monitoring in early diagnosis of ectopic pregnancy

Objective To explore the value of progesterone and serum β-HCG in the early diagnosis of ectopic pregnancy.Methods Progesterone and serum β-HCG were detected in 42 cases of suspected to be ectopic pregnancy and 40 women of regular intrauterine gestation.Results The progesterone and serum β-HCG value in the ectopic pregnancy group were obviously lower than those in the intrauterine gestation group,difference between the two groups showing statistical significance(P<0.01).With progesterone <15 ng/mL as the cut-off point for diagnosing ectopic pregnancy,its sensitivity and the specificity were 90.48% and 92.50% respectively,the positive predictive value was 92.68% and the diagnosis coincidence rate was 91.46% in the diagnosis of ectopic pregnancy.Conclusion The united monitoring of progesterone and serum β-HCG can enhance the sensitivity and the specificity in the early diagnosis of ectopic pregnancy.